Reactome | PRCC [nucleoplasm]

PRCC [nucleoplasm]

Stable Identifier

R-HSA-8867896

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Proline-rich protein PRCC, PRCC_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q92733 PRCC

Gene Names

PRCC, TPRC

Chain

chain:1-491

Reference Genes

BioGPS Gene:5546 PRCC

COSMIC (genes):PRCC PRCC

CTD Gene:5546 PRCC

dbSNP Gene:5546 PRCC

ENSEMBL:ENSG00000143294 PRCC

HGNC:9343 PRCC

KEGG Gene (Homo sapiens):5546 PRCC

Monarch:5546 PRCC

NCBI Gene:5546 PRCC

OMIM:179755 PRCC

UCSC:Q92733 PRCC

Reference Transcript

RefSeq:NM_005973.4 PRCC

Other Identifiers

0001770609

11716336_a_at

16672170

208938_at

2361735

2361736

2361737

2361738

2361739

2361740

2361741

2361744

2361745

2361748

2361749

2361750

2361752

2361754

2361755

2361756

39149_at

5546

7906235

A_23_P23411

GE60221

GO:0000398

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0006397

GO:0007049

GO:0008150

GO:0016607

GO:0034641

GO:0043226

GO:0051726

HMNXSV003021590

ILMN_1802843

ILMN_1809818

PH_hs_0000993

TC01001327.hg

X99720_rna1_at

g13436211_3p_x_at

Participates

as an input of

Formation of the Spliceosomal B Complex (Homo sapiens)

as a component of

Inferred To

Prcc [nucleoplasm] (Mus musculus)

Prcc [nucleoplasm] (Rattus norvegicus)

Dmel\CG17249 [nucleoplasm] (Drosophila melanogaster)

prcc [nucleoplasm] (Danio rerio)

Ghost homologue of PRCC [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of PRCC [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of PRCC [nucleoplasm] (Xenopus tropicalis)

prcc-1 [nucleoplasm] (Caenorhabditis elegans)

PRCC [nucleoplasm] (Canis familiaris)

PRCC [nucleoplasm] (Gallus gallus)

PRCC [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_005964.3

OpenTargets

ENSG00000143294

HPA

ENSG00000143294-PRCC

GeneCards

Q92733

Ensembl

ENSP00000271526, ENSG00000143294, ENST00000271526

PRO

Q92733

Pharos - Targets

Q92733

GlyGen

Q92733

Orphanet

15134

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38302 NTC20			0.556	3
UniProt:Q9NSC5 HOMER3	1	HOMER3 [cytosol] (R-HSA-6794236)	0.556	3
UniProt:P00533 EGFR	59	p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR M766_A767insASV [plasma membrane] (R-HSA-1996343) p-6Y-EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996342) p-6Y-EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541) p-6Y-EGFR A289V [plasma membrane] (R-HSA-1996334) p-6Y-EGFR T263P [plasma membrane] (R-HSA-1996336) p-6Y-EGFR G598V [plasma membrane] (R-HSA-1996339) p-6Y-EGFR R108K [plasma membrane] (R-HSA-1996338) p-6Y-EGFR A289T [plasma membrane] (R-HSA-1996341) p-6Y-EGFR G719C [plasma membrane] (R-HSA-1177530) p-6Y-EGFR A289D [plasma membrane] (R-HSA-1996340) p-6Y-EGFR G719A [plasma membrane] (R-HSA-1177528) EGFR L858R;T790M [plasma membrane] (R-HSA-1181386) EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1181399) EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996322) EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996325) EGFR M766_A767insASV [plasma membrane] (R-HSA-1996326) EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996317) EGFR L858R [plasma membrane] (R-HSA-1173212) EGFR G719S [plasma membrane] (R-HSA-1169418) EGFR E746_A750del [plasma membrane] (R-HSA-1181211) EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228010) EGFR A289V [plasma membrane] (R-HSA-1996321) EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228012) EGFR L747_T751del [plasma membrane] (R-HSA-1228015) EGFR A289D [plasma membrane] (R-HSA-1996327) EGFR L861Q [plasma membrane] (R-HSA-1177542) EGFR R108K [plasma membrane] (R-HSA-1996330) EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228034) EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228031) EGFR G719A [plasma membrane] (R-HSA-1177532) EGFR A289T [plasma membrane] (R-HSA-1996306) EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228025) EGFR G719C [plasma membrane] (R-HSA-1177531) EGFR T263P [plasma membrane] (R-HSA-1996315) EGFR G598V [plasma membrane] (R-HSA-1996314) EGFR L747_S752del [plasma membrane] (R-HSA-1228016) EGFR [endosome membrane] (R-HSA-9611160) p-4Y-EGFR [plasma membrane] (R-HSA-180287) p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR [plasma membrane] (R-HSA-8864019) p-Y1086,Y1101-EGFR [plasma membrane] (R-HSA-179868) EGFR [plasma membrane] (R-HSA-179837) p-6Y-EGFR [plasma membrane] (R-HSA-179803)	0.553	2

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