Reactome | PRPF40A [nucleoplasm]

PRPF40A [nucleoplasm]

Stable Identifier

R-HSA-8867890

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Pre-mRNA-processing factor 40 homolog A, PR40A_HUMAN, FBP11

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O75400 PRPF40A

Gene Names

PRPF40A, FBP11, FLAF1, FNBP3, HIP10, HYPA, HSPC225

Chain

chain:1-957

Reference Genes

BioGPS Gene:55660 PRPF40A

COSMIC (genes):PRPF40A PRPF40A

CTD Gene:55660 PRPF40A

dbSNP Gene:55660 PRPF40A

ENSEMBL:ENSG00000196504.20 PRPF40A

HGNC:16463 PRPF40A

KEGG Gene (Homo sapiens):55660 PRPF40A

Monarch:55660 PRPF40A

NCBI Gene:55660 PRPF40A

OMIM:612941 PRPF40A

UCSC:O75400 PRPF40A

Reference Transcript

RefSeq:NM_017892.3 PRPF40A

Other Identifiers

11743385_a_at

213729_PM_at

213729_at

214941_PM_s_at

214941_s_at

2581579

2581580

2581581

2581582

2581583

2581585

2581586

2581587

2581588

2581589

2581590

2581593

2581595

2581598

2581603

2581605

2581606

37506_at

37507_i_at

55660

GE85206

GO:0000398

GO:0000910

GO:0003723

GO:0005515

GO:0005622

GO:0005634

GO:0005654

GO:0005685

GO:0006397

GO:0007010

GO:0007049

GO:0008360

GO:0008380

GO:0016020

GO:0016071

GO:0016363

GO:0016477

GO:0016607

GO:0032465

GO:0032991

GO:0043226

GO:0045292

GO:0048856

GO:0048870

GO:0051301

GO:0071004

Hs.119325.0.S1_3p_at

Hs.119325.1.S1_3p_a_at

ILMN_1659854

TC02004643.hg

TC02004644.hg

Participates

as an output of

Formation of the Spliceosomal B complex (new) (Homo sapiens)

as an input of

Formation of the Spliceosomal E complex (update) (Homo sapiens)

as a component of

Inferred To

prp40 [nucleoplasm] (Schizosaccharomyces pombe)

prpf40a [nucleoplasm] (Xenopus tropicalis)

PRPF40A [nucleoplasm] (Bos taurus)

PRPF40A [nucleoplasm] (Caenorhabditis elegans)

PRPF40A [nucleoplasm] (Canis familiaris)

PRPF40A [nucleoplasm] (Danio rerio)

PRPF40A [nucleoplasm] (Dictyostelium discoideum)

PRPF40A [nucleoplasm] (Gallus gallus)

PRPF40A [nucleoplasm] (Plasmodium falciparum)

PRPF40A [nucleoplasm] (Sus scrofa)

Prp40 [nucleoplasm] (Drosophila melanogaster)

Prpf40a [nucleoplasm] (Mus musculus)

Prpf40a [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_060362.3

OpenTargets

ENSG00000196504

GeneCards

O75400

HPA

ENSG00000196504-PRPF40A

Ensembl

ENSG00000196504, ENST00000354363, ENSP00000346332

PRO

O75400

Pharos - Targets

O75400

PDB

2DYF, 2KZG, 1UZC, 1YWI, 1ZR7, 2LKS, 2L5F, 2CQN, 2L9V, 1YWJ

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.743	15
UniProt:Q9BUJ2 HNRNPUL1	1	HNRNPUL1 [nucleoplasm] (R-HSA-72106)	0.553	2
UniProt:Q9NRR5 UBQL4			0.553	2
UniProt:Q9H190 SDCB2			0.553	2
UniProt:Q53F19 NCBP3			0.527	2
UniProt:Q15459 SF3A1	1	SF3A1 [nucleoplasm] (R-HSA-71962)	0.508	2
UniProt:Q12873 CHD3	2	CHD3 [nucleoplasm] (R-HSA-4657012) monoSUMO1-K1971-CHD3 [nucleoplasm] (R-HSA-8956372)	0.508	2
UniProt:Q8N5F7 NKAP	1	NKAP [nucleoplasm] (R-HSA-9769602)	0.508	2
UniProt:Q15637 SF1	1	SF1 [nucleoplasm] (R-HSA-8865928)	0.482	3

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