Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
OSBPL5 [cytosol]
Stable Identifier
R-HSA-8867856
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Oxysterol-binding protein-related protein 5, OSBL5_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Acyl chain remodelling of PS (Homo sapiens)
OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Homo sapiens)
OSBPL5,8,10 [cytosol] (Homo sapiens)
OSBPL5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H0X9 OSBPL5
Gene Names
OSBPL5, KIAA1534, OBPH1, ORP5
Chain
chain:1-879
Reference Genes
BioGPS Gene:114879 OSBPL5
COSMIC (genes):OSBPL5 OSBPL5
CTD Gene:114879 OSBPL5
dbSNP Gene:114879 OSBPL5
ENSEMBL:ENSG00000021762 OSBPL5
HGNC:16392 OSBPL5
KEGG:hsa:114879 OSBPL5
Monarch:114879 OSBPL5
NCBI Gene:114879 OSBPL5
OMIM:606733 OSBPL5
UCSC:Q9H0X9 OSBPL5
Reference Transcript
RefSeq:XM_011519873.2 OSBPL5
RefSeq:NM_001144063.1 OSBPL5
RefSeq:XM_017017163.1 OSBPL5
RefSeq:NM_020896.3 OSBPL5
RefSeq:NM_145638.2 OSBPL5
Other Identifiers
114879
11735162_a_at
11735163_x_at
11735164_a_at
11735165_s_at
11735166_x_at
11739089_x_at
11749720_x_at
11756697_a_at
11756752_a_at
16734570
223464_PM_at
223464_at
233734_PM_s_at
233734_s_at
3359600
3359602
3359603
3359605
3359607
3359608
3359609
3359611
3359612
3359613
3359614
3359615
3359616
3359619
3359620
3359623
3359624
3359625
3359626
3359629
3359630
3359631
3359632
3359633
3359634
3359635
3359636
3359637
3359638
3359639
3359640
3359641
3359642
3359652
3359658
3359659
3359660
59331_at
7945831
A_23_P53081
A_33_P3394972
GE63358
GO:0001786
GO:0005215
GO:0005548
GO:0005783
GO:0005789
GO:0005829
GO:0006575
GO:0006629
GO:0006869
GO:0006893
GO:0008142
GO:0008203
GO:0008289
GO:0015485
GO:0015914
GO:0016020
GO:0016192
GO:0030301
GO:0032934
GO:0036150
GO:0043226
GO:0043231
GO:0061024
GO:0070273
GO:0120009
GO:0140268
GO:0140343
HMNXSV003048423
Hs.112034.1.S1_3p_a_at
ILMN_1802151
ILMN_2307032
PH_hs_0023698
TC11001291.hg
TC11003011.hg
g12053330_3p_at
p33857
Participates
as a member of
OSBPL5,8,10 [cytosol] (Homo sapiens)
Inferred To
osbG [cytosol]
(Dictyostelium discoideum)
obr-3 [cytosol]
(Caenorhabditis elegans)
osbJ [cytosol]
(Dictyostelium discoideum)
osbD [cytosol]
(Dictyostelium discoideum)
osbC [cytosol]
(Dictyostelium discoideum)
Orp8 [cytosol]
(Drosophila melanogaster)
Osbpl5 [cytosol]
(Rattus norvegicus)
osbB [cytosol]
(Dictyostelium discoideum)
osbE [cytosol]
(Dictyostelium discoideum)
osbA [cytosol]
(Dictyostelium discoideum)
Homologues of OSBPL5 [cytosol]
(Dictyostelium discoideum)
OSBPL5 [cytosol]
(Bos taurus)
OSBPL5 [cytosol]
(Canis familiaris)
OSBPL5 [cytosol]
(Gallus gallus)
OSBPL5 [cytosol]
(Mus musculus)
OSBPL5 [cytosol]
(Saccharomyces cerevisiae)
OSBPL5 [cytosol]
(Schizosaccharomyces pombe)
OSBPL5 [cytosol]
(Sus scrofa)
osbL [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001137535.1
,
XP_011518175.1
,
NP_065947.1
,
NP_663613.1
,
XP_016872652.1
ENSEMBL
ENSP00000263650
,
ENST00000348039
,
ENST00000389989
,
ENSP00000374639
,
ENST00000525498
,
ENST00000263650
,
ENSP00000433342
,
ENSP00000302872
OpenTargets
ENSG00000021762
HPA
ENSG00000021762-OSBPL5
PRO
Q9H0X9
Pharos - Targets
Q9H0X9
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54802 NAGLU
5
NAGLU R674C [lysosomal lumen]
(R-HSA-2219558)
NAGLU R674H [lysosomal lumen]
(R-HSA-2219557)
NAGLU R626* [lysosomal lumen]
(R-HSA-2219568)
NAGLU R297* [lysosomal lumen]
(R-HSA-2219553)
NAGLU(59-743) [lysosomal lumen]
(R-HSA-1678772)
0.527
4
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text