Reactome | SYCE3 [nucleoplasm]

SYCE3 [nucleoplasm]

Stable Identifier

R-HSA-8867779

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Synaptonemal complex central element protein 3, SYCE3_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9NX40 OCAD1

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External Reference Information

External Reference

UniProt:A1L190 SYCE3

Gene Names

SYCE3, C22orf41, THEG2

Chain

chain:1-88

Reference Genes

BioGPS Gene:644186 SYCE3

COSMIC (genes):SYCE3 SYCE3

CTD Gene:644186 SYCE3

dbSNP Gene:644186 SYCE3

ENSEMBL:ENSG00000217442 SYCE3

ENSEMBL_homo_sapiens_GENE:ENSG00000217442.4 SYCE3

HGNC:35245 SYCE3

KEGG Gene (Homo sapiens):644186 SYCE3

Monarch:644186 SYCE3

NCBI Gene:644186 SYCE3

OMIM:615775 SYCE3

UCSC:A1L190 SYCE3

Reference Transcript

RefSeq:NM_001123225.2 SYCE3

Other Identifiers

11732717_at

16936643

239854_PM_at

239854_at

3966049

3966050

3966051

3966052

3966053

644186

A_33_P3250887

GE479566

GO:0000228

GO:0000801

GO:0005515

GO:0005634

GO:0005694

GO:0006310

GO:0006915

GO:0007049

GO:0007059

GO:0007130

GO:0007131

GO:0007283

GO:0012501

GO:0022414

GO:0030154

GO:0035234

GO:0043065

GO:0043226

GO:0048856

GO:0051094

GO:0051301

GO:0051321

GO:0140013

GO:2000243

HMNXSV003014313

Hs.98579.0.A1_3p_at

TC22000916.hg

Participates

as a component of

Central Element of Synaptonemal Complex [nucleoplasm] (Homo sapiens)

as an input of

Synapsis (Homo sapiens)

Cross References

RefSeq

NP_001116697.1

OpenTargets

ENSG00000217442

GeneCards

A1L190

HPA

ENSG00000217442-SYCE3

Ensembl

ENSG00000217442, ENST00000402753, ENSP00000385122, ENSP00000385480, ENST00000406915

PRO

A1L190

Pharos - Targets

A1L190

Interactors (38)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96CS2 HAUS1	1	HAUS1 [cytosol] (R-HSA-8855199)	0.666	4
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	15
UniProt:Q16512 PKN1	3	p-T774-PKN1 [nucleoplasm] (R-HSA-5625721) p-T774-PKN1 [cytosol] (R-HSA-5623651) PKN1 [cytosol] (R-HSA-5623613)	0.556	3
IntAct:EBI-25865403 EHD27213144			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:Q9UL45 BLOC1S6	1	BLOC1S6 [cytosol] (R-HSA-429816)	0.556	3
UniProt:Q5XKE5 KRT79	1	KRT79 [cytosol] (R-HSA-6809643)	0.556	3
UniProt:P60891 PRPS1	1	PRPS1 [cytosol] (R-HSA-73483)	0.556	3
UniProt:Q9BVL2 NUP58			0.556	3
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q96NL6 SCLT1	1	SCLT1 [cytosol] (R-HSA-5620935)	0.527	3
UniProt:Q9NRK6 ABCB10	1	ABCB10 [mitochondrial inner membrane] (R-HSA-1369015)	0.527	2
UniProt:O96011 PEX11B	2	PEX11B [peroxisomal membrane] (R-HSA-9625561) PEX11B [cytosol] (R-HSA-9625562)	0.527	3
UniProt:Q02224 CENPE	1	CENPE [cytosol] (R-HSA-376245)	0.527	3
UniProt:Q86YM7 HOMER1	1	HOMER1 [cytosol] (R-HSA-6794264)	0.527	3
UniProt:Q2Q1W2 TRIM71	1	TRIM71 [cytosol] (R-HSA-5688972)	0.527	3
UniProt:Q9NX40 OCAD1			0.527	3
UniProt:Q68CZ6 HAUS3	1	HAUS3 [cytosol] (R-HSA-8855201)	0.527	3
UniProt:Q9H3R5 CENPH	2	CENPH [nucleoplasm] (R-HSA-606314) CENPH [cytosol] (R-HSA-375294)	0.527	2
UniProt:Q86VS8 HOOK3			0.527	3
UniProt:Q6ZN16 M3K15			0.527	2
UniProt:O95229 ZWINT	1	ZWINT [cytosol] (R-HSA-376254)	0.527	3
UniProt:Q9GZM5 YIPF3			0.527	3
UniProt:Q13617 CUL2	3	G76-NEDD8-K689-CUL2 [cytosol] (R-HSA-8952511) CUL2 [nucleoplasm] (R-HSA-1234126) CUL2 [cytosol] (R-HSA-416982)	0.527	3
UniProt:Q96R06 SPAG5			0.527	4
UniProt:Q9UK73 FEM1B	1	FEM1B [cytosol] (R-HSA-201572)	0.527	4
UniProt:Q9H9Q2 COPS7B	2	COPS7B [cytosol] (R-HSA-416966) COPS7B [nucleoplasm] (R-HSA-5697023)	0.527	3
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.527	3
UniProt:Q6UVJ0 SAS6			0.527	3
UniProt:P02008 HBAZ			0.527	2
UniProt:Q5VIR6 VPS53	1	VPS53 [trans-Golgi network membrane] (R-HSA-6811031)	0.527	2
UniProt:Q96E52 OMA1	3	OMA1(144-447) [mitochondrial inner membrane] (R-HSA-9840539) OMA1(144-524) [mitochondrial inner membrane] (R-HSA-9840540) OMA1 [mitochondrial inner membrane] (R-HSA-8867510)	0.527	2
UniProt:Q9Y2V7 COG6	2	COG6 [Golgi membrane] (R-HSA-2980958) COG6 [trans-Golgi network membrane] (R-HSA-6813872)	0.527	3
UniProt:O94927 HAUS5	1	HAUS5 [cytosol] (R-HSA-8855197)	0.527	3
UniProt:O15258 RER1			0.527	3
UniProt:Q9NVX0 HAUS2	1	HAUS2 [cytosol] (R-HSA-380274)	0.527	3
UniProt:Q7L5N1 COPS6	2	COPS6 [nucleoplasm] (R-HSA-5697026) COPS6 [cytosol] (R-HSA-416961)	0.527	3

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