Reactome | L-isoglutamyl polyglycyl-TUBA3E [cytosol]

L-isoglutamyl polyglycyl-TUBA3E [cytosol]

Stable Identifier

R-HSA-8867388

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

TUBA3E, Tubulin alpha-3E chain, TBA3E_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Carboxyterminal post-translational modifications of tubulin (Homo sapiens)
    - TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Homo sapiens)
      - Polyglycylated microtubule [cytosol] (Homo sapiens)
        
        Polyglycylated microtubule protofilament [cytosol] (Homo sapiens)
        
        Polyglycyl alpha-beta tubulin dimer [cytosol] (Homo sapiens)
        
        Polyglycyl alpha tubulin:GTP [cytosol] (Homo sapiens)
        
        Polyglycyl alpha tubulin [cytosol] (Homo sapiens)
        
        L-isoglutamyl polyglycyl-TUBA3E [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q6PEY2 TUBA3E

Gene Names

TUBA3E

Chain

chain:1-450, chain:1-449

Reference Genes

BioGPS Gene:112714 TUBA3E

COSMIC (genes):TUBA3E TUBA3E

CTD Gene:112714 TUBA3E

dbSNP Gene:112714 TUBA3E

ENSEMBL:ENSG00000152086 TUBA3E

HGNC:20765 TUBA3E

KEGG:hsa:112714 TUBA3E

Monarch:112714 TUBA3E

NCBI Gene:112714 TUBA3E

OMIM:619918 TUBA3E

UCSC:Q6PEY2 TUBA3E

Reference Transcript

RefSeq:NM_207312.2 TUBA3E

Other Identifiers

112714

11733986_x_at

16902787

216323_PM_x_at

216323_x_at

2506190

2506192

2506193

2506194

2506195

2506197

2506198

2506199

2575950

2575951

2575952

2575953

2575954

2575955

2575957

2575958

2575959

2575960

2575961

3503754

3503762

685_f_at

8045291

8055194

GE543435

GO:0000226

GO:0000278

GO:0003674

GO:0003824

GO:0005198

GO:0005200

GO:0005515

GO:0005525

GO:0005634

GO:0005737

GO:0005856

GO:0005874

GO:0007010

GO:0007017

GO:0008150

GO:0015630

GO:0016787

GO:0043226

GO:0046872

HMNXSV003012336

HMNXSV003057359

ILMN_1652464

PH_hs_0033321

TC02002321.hg

Participates

as a candidate of

Polyglycyl alpha tubulin [cytosol] (Homo sapiens)

Other forms of this molecule

Ack-TUBA3E [cytosol]

TUBA3E folding intermediate [cytosol]

TUBA3E unfolded [cytosol]

Polyglutamyl-TUBA3E [cytosol]

TUBA3E(1-449) [cytosol]

TUBA3E [cytosol]

Inferred To

Homologues of L-isoglutamyl polyglycyl-TUBA3E [cytosol] (Dictyostelium discoideum)

L-isoglutamyl polyglycyl-TUBA3E [cytosol] (Dictyostelium discoideum)

L-isoglutamyl polyglycyl-TUBA3C [cytosol] (Dictyostelium discoideum)

L-isoglutamyl polyglycyl-TUBA3C [cytosol] (Plasmodium falciparum)

Homologues of L-isoglutamyl polyglycyl-TUBA3C [cytosol] (Plasmodium falciparum)

Modified Residues

Name

L-isoglutamyl-polyglycine at unknown position

PsiMod Name

L-isoglutamyl-polyglycine

PsiMod Definition

A protein modification that effectively converts an L-glutamic acid residue to L-isoglutamyl-polyglycine.

Cross References

RefSeq

NP_997195.1

ENSEMBL

ENSP00000318197, ENST00000312988

OpenTargets

ENSG00000152086

HPA

ENSG00000152086-TUBA3E

PRO

Q6PEY2

Pharos - Targets

Q6PEY2

GlyGen

Q6PEY2

HMDB Protein

HMDBP08597

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13287 NMI	1	NMI [cytosol] (R-HSA-9731022)	0.718	9

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