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pre-VLDL translocates from RER membrane to SER lumen
Stable Identifier
R-HSA-8866308
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
smooth endoplasmic reticulum
,
endoplasmic reticulum membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein assembly (Homo sapiens)
VLDL assembly (Homo sapiens)
pre-VLDL translocates from RER membrane to SER lumen (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
For the formation of bona fide VLDL, pre-VLDL must translocate from the rough ER membrane to smooth ER lumen where it acquires the major lipids (Olofsson et al. 2000).
Literature References
PubMed ID
Title
Journal
Year
11369260
Intracellular assembly of VLDL: two major steps in separate cell compartments
Asp, L
,
Olofsson, SO
,
Stillemark-Billton, P
Trends Cardiovasc. Med.
2000
Participants
Input
pre-VLDL [endoplasmic reticulum membrane]
(Homo sapiens)
Output
pre-VLDL [smooth endoplasmic reticulum]
(Homo sapiens)
Participates
as an event of
VLDL assembly (Homo sapiens)
Orthologous Events
pre-VLDL translocates from RER membrane to SER lumen (Bos taurus)
pre-VLDL translocates from RER membrane to SER lumen (Canis familiaris)
pre-VLDL translocates from RER membrane to SER lumen (Gallus gallus)
pre-VLDL translocates from RER membrane to SER lumen (Mus musculus)
pre-VLDL translocates from RER membrane to SER lumen (Rattus norvegicus)
pre-VLDL translocates from RER membrane to SER lumen (Sus scrofa)
Authored
Jassal, B (2016-03-30)
Reviewed
D'Eustachio, P (2016-04-05)
Created
Jassal, B (2016-03-30)
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