Reactome | RBM17 [nucleoplasm]

RBM17 [nucleoplasm]

Stable Identifier

R-HSA-8865891

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Splicing factor 45, SPF45_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96I25 RBM17

Gene Names

RBM17, SPF45

Chain

initiator methionine:, chain:2-401

Reference Genes

BioGPS Gene:84991 RBM17

COSMIC (genes):RBM17 RBM17

CTD Gene:84991 RBM17

dbSNP Gene:84991 RBM17

ENSEMBL:ENSG00000134453 RBM17

ENSEMBL_homo_sapiens_GENE:ENSG00000134453.16 RBM17

HGNC:16944 RBM17

KEGG Gene (Homo sapiens):84991 RBM17

Monarch:84991 RBM17

NCBI Gene:84991 RBM17

OMIM:606935 RBM17

UCSC:Q96I25 RBM17

Reference Transcript

Other Identifiers

11721677_a_at

11721678_a_at

11721679_a_at

11733843_a_at

16702147

224780_PM_at

224780_at

224781_PM_s_at

224781_s_at

225751_PM_at

225751_at

3233548

3233549

3233550

3233551

3233552

3233553

3233558

3233559

3233560

3233561

3233564

3233567

3233570

3233573

3233577

3233579

3233581

3233582

3233583

3233584

3233585

3233586

3233587

3233588

3233589

3617985

3617990

3617991

49221_s_at

56356_at

7926021

84991

A_23_P35645

A_23_P35650

A_23_P423315

GE80333

GE86522

GO:0000380

GO:0000398

GO:0003676

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0006397

GO:0008380

GO:0016071

GO:0032991

GO:0043226

GO:0045292

HMNXSV003034450

Hs.107001.0.S1_3p_a_at

Hs.107001.0.S2_3p_at

Hs.107001.1.S1_3p_at

ILMN_1781906

PH_hs_0005949

TC10000052.hg

Participates

as a component of

Inferred To

rbm-17 [nucleoplasm] (Caenorhabditis elegans)

Rbm17 [nucleoplasm] (Mus musculus)

Rbm17 [nucleoplasm] (Rattus norvegicus)

rbm17 [nucleoplasm] (Xenopus tropicalis)

Ghost homologue of RBM17 [nucleoplasm] (Danio rerio)

Ghost homologue of RBM17 [nucleoplasm] (Schizosaccharomyces pombe)

RBM17 [nucleoplasm] (Bos taurus)

RBM17 [nucleoplasm] (Canis familiaris)

RBM17 [nucleoplasm] (Dictyostelium discoideum)

RBM17 [nucleoplasm] (Gallus gallus)

RBM17 [nucleoplasm] (Plasmodium falciparum)

RBM17 [nucleoplasm] (Sus scrofa)

Spf45 [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_001139019.1, NP_116294.1

OpenTargets

ENSG00000134453

HPA

ENSG00000134453-RBM17

GeneCards

Q96I25

Ensembl

ENSP00000369218, ENST00000446108, ENSP00000388638, ENSG00000134453, ENST00000379888

PRO

Q96I25

Pharos - Targets

Q96I25

PDB

2PE8, 5LSO, 6HIP, 2PEH

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P21673 SAT1	1	SAT1 [cytosol] (R-HSA-351236)	0.87	13
UniProt:O43143 DHX15	1	DHX15 [nucleoplasm] (R-HSA-5688097)	0.844	11
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.83	8
UniProt:O75533 SF3B1	1	SF3B1 [nucleoplasm] (R-HSA-71968)	0.737	4
UniProt:Q15637 SF1	1	SF1 [nucleoplasm] (R-HSA-8865928)	0.73	8
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P36957 DLST	4	Lipo-K110-DLST [mitochondrial matrix] (R-HSA-69993) SuccinyllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853502) LipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853485) DLST [mitochondrial matrix] (R-HSA-6792574)	0.556	3
UniProt:P16284 PECAM1	4	PECAM1 [plasma membrane] (R-HSA-114686) p-Y663,Y686-PECAM1(27-?) [plasma membrane] (R-HSA-210007) PECAM1 [secretory granule membrane] (R-HSA-6804778) PECAM1 [platelet alpha granule membrane] (R-HSA-61489)	0.556	3
UniProt:P27797 CALR	6	CALR [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [phagocytic vesicle membrane] (R-HSA-1236879) CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448)	0.556	3
UniProt:Q8IWZ8 SUGP1	1	SUGP1 [nucleoplasm] (R-HSA-72043)	0.508	2

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