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p-STAT5 dimers bind the BRWD1 gene promoter
Stable Identifier
R-HSA-8865626
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-7 signaling (Homo sapiens)
p-STAT5 dimers bind the BRWD1 gene promoter (Homo sapiens)
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Based on mouse studies Signal transducer and activator of transcription 5A or 5B (STAT5A or STAT5B), activated as a result of interleukin-7 (IL7) signaling, binds to the Bromodomain and WD repeat-containing protein 1 (BRWD1) promoter in pro-B cells (Mandal et al. 2015).
Participants
Input
BRWD1 gene [nucleoplasm]
(Homo sapiens)
p-STAT5 dimer [nucleoplasm]
(Homo sapiens)
Output
2x(p-STAT5A,p-STAT5B):BRWD1 gene [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Interleukin-7 signaling (Homo sapiens)
Inferred From
Phosphorylated Stat5 dimers bind the Brwd1 gene promoter (Mus musculus)
Authored
Orlic-Milacic, M (2016-03-23)
Reviewed
Mandal, M (2016-05-11)
Created
Orlic-Milacic, M (2016-03-23)
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