BRWD1 binds SMARCA4

Stable Identifier
R-HSA-8865605
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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BRWD1 (WDR9) is a nuclear protein with eight WD repeats at the N-terminus and 2 centrally located bromodomains. BRWD1 is thought to be involved in chromatin remodelling and transcriptional regulation. BRWD1 binds to Transcription activator BRG1 (SMARCA4 or BRG1), a component of the SWI/SNF complex(Huang et al. 2003). Similar to BRWD1 (Mandal et al. 2015), SMARCA4 is also implicated in B-cell development (Choi et al. 2012, Bossen et al. 2015).

Literature References
PubMed ID Title Journal Year
12889071 Expression of the Wdr9 gene and protein products during mouse development

Huang, H, Rambaldi, I, Daniels, E, Featherstone, M

Dev. Dyn. 2003
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