Reactome | TFAP2A homodimer:CDKN1A gene [nucleoplasm]

Reactome will be unavailable due to host maintenance from Friday, April 27 at 6pm to Sunday, April 29 at 11:55pm.

During the outage, you may wish to use our mirror site at reactome.ncpsb.org.

Stable Identifier

R-HSA-8865245

Type

Complex

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Literature References

PubMed ID	Title	Journal	Year
19798054	AP-2gamma promotes proliferation in breast tumour cells by direct repression of the CDKN1A gene	EMBO J.	2009
8988173	AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression	Nat. Genet.	1997
21084835	Dual association by TFAP2A during activation of the p21cip/CDKN1A promoter	Cell Cycle	2010

Participants

components

Participant Of

output

This entity regulates

Positive Regulation