OTUD7A hydrolyses K11diUb

Stable Identifier
R-HSA-8865182
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

OTU domain-containing protein 7A (CEZANNE2, OTUD7A ) has deubiquitinating activity that is specific for Lys11 ubiquitin linkages (Mevissen et al 2013).

Literature References
PubMed ID Title Journal Year
23827681 OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

Elliott, PR, Kulathu, Y, Geurink, PP, Hospenthal, MK, Ekkebus, R, Freund, SM, Mevissen, TE, Arnaudo, N, El Oualid, F, Ovaa, H, Wauer, T, Komander, D, Akutsu, M

Cell 2013
Participants
Participates
Catalyst Activity

thiol-dependent deubiquitinase activity of OTUD7A [cytosol]

Orthologous Events
Authored
Reviewed
Created
Cite Us!