TFAP2A,TFAP2C homodimers stimulate CGA gene expression

Stable Identifier
R-HSA-8864433
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
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Summation

Homodimers of AP-2 family transcription factors TFAP2A (AP-2 alpha) and TFAP2C (AP-2 gamma) directly stimulate CGA (chorionic gonadotropin alpha) transcription by binding to the CGA promoter (Johnson et al. 1997, LiCalsi et al. 2000).

Literature References
PubMed ID Title Journal Year
10648798 AP-2 family members regulate basal and cAMP-induced expression of human chorionic gonadotropin

LiCalsi, C, Christophe, S, Steger, DJ, Buescher, M, Fischer, W, Mellon, PL

Nucleic Acids Res. 2000
9182571 Regulation of the human chorionic gonadotropin alpha- and beta-subunit promoters by AP-2

Johnson, W, Albanese, C, Handwerger, S, Williams, T, Pestell, RG, Jameson, JL

J. Biol. Chem. 1997
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