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Ub-C91-UBE2W [nucleoplasm]
Stable Identifier
R-HSA-8864205
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Ubiquitin-conjugating enzyme E2 W ecNumber evidence="7"2.3.2.23/ecNumber, UBE2W_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)
UBA1 conjugates ubiquitin to nuclear E2 enzymes (Homo sapiens)
Ub:E2 (UBA1 substrate) [nucleoplasm] (Homo sapiens)
Ub-conjugated E2 enzyme (UBA1 substrate) [nucleoplasm] (Homo sapiens)
Ub-C91-UBE2W [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96B02 UBE2W
Gene Names
UBE2W, UBC16
Chain
chain:1-151
Reference Genes
BioGPS Gene:55284 UBE2W
COSMIC (genes):UBE2W UBE2W
CTD Gene:55284 UBE2W
dbSNP Gene:55284 UBE2W
ENSEMBL:ENSG00000104343 UBE2W
HGNC:25616 UBE2W
KEGG Gene (Homo sapiens):55284 UBE2W
Monarch:55284 UBE2W
NCBI Gene:55284 UBE2W
OMIM:614277 UBE2W
UCSC:Q96B02 UBE2W
Reference Transcript
RefSeq:NM_001001481.2 UBE2W
RefSeq:NM_018299.4 UBE2W
RefSeq:NM_001271015.1 UBE2W
Other Identifiers
0002850707
11727805_a_at
11727806_s_at
11750058_a_at
1555217_PM_at
1555217_at
17078330
218521_PM_s_at
218521_s_at
222656_PM_at
222656_at
222657_PM_s_at
222657_s_at
241887_PM_at
241887_at
3140765
3140766
3140767
3140768
3140769
3140770
3140771
3140772
3140773
3140774
3140775
3140776
3140777
3140781
3140783
3140784
3140788
3140792
3140804
3140808
41923_at
46903_at
55284
59735_at
60199_at
60791_at
68729_at
77467_at
8151401
A_23_P71430
A_23_P71433
GE55943
GE650636
GE852485
GO:0000166
GO:0000209
GO:0003674
GO:0004842
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0006259
GO:0006281
GO:0006464
GO:0006513
GO:0006515
GO:0006950
GO:0006974
GO:0008150
GO:0009056
GO:0016567
GO:0016740
GO:0019899
GO:0031625
GO:0034641
GO:0043161
GO:0043167
GO:0043226
GO:0061631
GO:0070979
GO:0071218
HMNXSV003006782
Hs.128841.0.A1_3p_at
Hs.21275.0.A1_3p_a_at
Hs.21275.0.A3_3p_at
Hs2.21275.2.S1_3p_at
ILMN_1717420
ILMN_1885131
ILMN_2376142
PH_hs_0024271
TC08002385.hg
TC08002587.hg
g8922821_3p_a_at
Participates
as a member of
Ub-conjugated E2 enzyme (UBA1 substrate) [nucleoplasm] (Homo sapiens)
Other forms of this molecule
UBE2W [nucleoplasm]
UBE2W [cytosol]
Inferred To
Ube2w [nucleoplasm]
(Mus musculus)
Ube2W [nucleoplasm]
(Drosophila melanogaster)
ube2wb [nucleoplasm]
(Danio rerio)
LOC103694506 [nucleoplasm]
(Rattus norvegicus)
UBE2W [nucleoplasm]
(Bos taurus)
UBE2W [nucleoplasm]
(Canis familiaris)
UBE2W [nucleoplasm]
(Gallus gallus)
UBE2W [nucleoplasm]
(Sus scrofa)
Homologues of Ub-C91-UBE2W [nucleoplasm]
(Rattus norvegicus)
Ub-C91-UBE2W [nucleoplasm]
(Plasmodium falciparum)
Ub-C91-UBE2W [nucleoplasm]
(Rattus norvegicus)
ube2w [nucleoplasm]
(Dictyostelium discoideum)
ube2w [nucleoplasm]
(Xenopus tropicalis)
ubc-16 [nucleoplasm]
(Caenorhabditis elegans)
Modified Residues
Name
S-(glycyl)-L-cysteine (Cys-Gly) at 91
Coordinate
91
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
NP_001257944.1
,
NP_001001481.2
,
NP_060769.4
OpenTargets
ENSG00000104343
HPA
ENSG00000104343-UBE2W
GeneCards
Q96B02
Ensembl
ENST00000651945
,
ENST00000602593
,
ENST00000517608
,
ENSP00000499153
,
ENSP00000428813
,
ENSP00000473561
,
ENSG00000104343
PRO
Q96B02
Pharos - Targets
Q96B02
PDB
2MT6
,
2A7L
HMDB Protein
HMDBP09293
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6ZNA4 RNF111
2
RNF111 [nucleoplasm]
(R-HSA-2186765)
RNF111 [cytosol]
(R-HSA-975981)
0.553
2
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