Reactome | Ub-C90-UBE2G1 [cytosol]

Ub-C90-UBE2G1 [cytosol]

Stable Identifier

R-HSA-8864149

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin-conjugating enzyme E2 G1, UB2G1_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Protein ubiquitination (Homo sapiens)
    - Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)
      - UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Homo sapiens)
        
        Ub:E2 (UBA1 substrate) [cytosol] (Homo sapiens)
        
        Ub-conjugated E2 enzyme (UBA1 substrate) [cytosol] (Homo sapiens)
        
        Ub-C90-UBE2G1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P62253 UBE2G1

Gene Names

UBE2G1, UBE2G

Chain

chain:1-170, initiator methionine:, chain:2-170

Reference Genes

BioGPS Gene:7326 UBE2G1

COSMIC (genes):UBE2G1 UBE2G1

CTD Gene:7326 UBE2G1

dbSNP Gene:7326 UBE2G1

ENSEMBL:ENSG00000132388 UBE2G1

ENSEMBL_homo_sapiens_GENE:ENSG00000132388.13 UBE2G1

HGNC:12482 UBE2G1

KEGG Gene (Homo sapiens):7326 UBE2G1

Monarch:7326 UBE2G1

NCBI Gene:7326 UBE2G1

OMIM:601569 UBE2G1

UCSC:P62253 UBE2G1

Reference Transcript

RefSeq:NM_003342.4 UBE2G1

Other Identifiers

11722027_s_at

11722028_at

1423_at

16840006

209141_PM_at

209141_at

209142_PM_s_at

209142_s_at

226005_PM_at

226005_at

3742062

3742064

3742066

3742068

3742069

3742070

3742071

3742072

3742073

3742078

3742079

3742083

3742090

3742092

3742102

3742103

3742104

37662_at

49474_at

7326

8011626

A_23_P27066

A_24_P296520

D78514_at

GE56908

GE57301

GO:0000166

GO:0000209

GO:0003824

GO:0004842

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005829

GO:0006511

GO:0016567

GO:0016740

GO:0019787

GO:0030163

GO:0031625

GO:0032446

GO:0036211

GO:0043161

GO:0043226

GO:0061631

GO:0070062

GO:0070534

GO:0070936

GO:0140096

HMNXSV003002792

HMNXSV003055294

Hs.296273.0.A1_3p_at

Hs.78563.0.A3_3p_at

ILMN_1719039

ILMN_1814465

ILMN_1886353

PH_hs_0004530

PH_hs_0005846

TC17001020.hg

g12803862_3p_a_at

Participates

as a member of

Ub-conjugated E2 enzyme (UBA1 substrate) [cytosol] (Homo sapiens)

Other forms of this molecule

UBE2G1 [cytosol]

Inferred To

ube2g1 [cytosol] (Xenopus tropicalis)

Ub-C90-UBE2G1 [cytosol] (Dictyostelium discoideum)

Ub-C90-UBE2G1 [cytosol] (Plasmodium falciparum)

ubc15 [cytosol] (Schizosaccharomyces pombe)

Homologues of Ub-C90-UBE2G1 [cytosol] (Plasmodium falciparum)

CDC34 [cytosol] (Saccharomyces cerevisiae)

UBE2G1 [cytosol] (Bos taurus)

UBE2G1 [cytosol] (Canis familiaris)

UBE2G1 [cytosol] (Gallus gallus)

UBE2G1 [cytosol] (Sus scrofa)

ubc-7 [cytosol] (Caenorhabditis elegans)

Ube2g1 [cytosol] (Mus musculus)

Ube2g1 [cytosol] (Rattus norvegicus)

BcDNA:RE63412 [cytosol] (Drosophila melanogaster)

ube2g2 [cytosol] (Danio rerio)

Modified Residues

Name

S-(glycyl)-L-cysteine (Cys-Gly) at 90

Coordinate

PsiMod Name

S-(glycyl)-L-cysteine (Cys-Gly)

PsiMod Definition

A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.

Cross References

RefSeq

NP_003333.1

OpenTargets

ENSG00000132388

GeneCards

P62253

HPA

ENSG00000132388-UBE2G1

Ensembl

ENST00000396981, ENSP00000380178, ENSG00000132388

PRO

P62253

Pharos - Targets

P62253

PDB

2AWF, 6D68

HMDB Protein

HMDBP00579

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06307 CCK	1	CCK [extracellular region] (R-HSA-388539)	0.556	3