PTPN18 binds ERBB2:EGFR heterodimers

Stable Identifier
R-HSA-8864105
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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PTPN18 protein tyrosine phosphatase (BDP1) binds ERBB2, activated in response to EGF stimulation, via PEST and catalytic domains of PTPN18 (Wang et al. 2014).

Literature References
PubMed ID Title Journal Year
25081058 The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes

Wang, HM, Xu, YF, Ning, SL, Yang, DX, Li, Y, Du, YJ, Yang, F, Zhang, Y, Liang, N, Yao, W, Zhang, LL, Gu, LC, Gao, CJ, Pang, Q, Chen, YX, Xiao, KH, Ma, R, Yu, X, Sun, JP

Cell Res. 2014
Participants
Participant Of
Orthologous Events
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Reviewed
Created