Fusion of ERC and phagosome

Stable Identifier
R-HSA-8863973
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
phagocytic vesicle membrane, recycling endosome membrane
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Fusion of ERC and phagosome
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Recycling endosome-localized R-SNARE protein like RAB11a, VAMP3, and VAMP8 dock with target phagosome membrane Q-SNARE protein SNAP23. MHC-I present on the recycling endosomes would be delivered to phagosomes during this process.

Literature References
PubMed ID Title Journal Year
25083866 TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation

Nair-Gupta, P, Baccarini, A, Tung, N, Seyffer, F, Florey, O, Huang, Y, Banerjee, M, Overholtzer, M, Roche, PA, Tampé, R, Brown, BD, Amsen, D, Whiteheart, SW, Blander, JM

Cell 2014
Participants
Input
Output
Participant Of
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Authored
Garapati, P V  (2016-03-10)
Reviewed
Bergeron, JJ  (2016-05-16)
Created
Garapati, P V  (2016-03-10)
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