Fusion of ERC and phagosome

Stable Identifier
R-HSA-8863973
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
phagocytic vesicle membrane, recycling endosome membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Fusion of ERC and phagosome
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Recycling endosome-localized R-SNARE protein like RAB11a, VAMP3, and VAMP8 dock with target phagosome membrane Q-SNARE protein SNAP23. MHC-I present on the recycling endosomes would be delivered to phagosomes during this process.

Literature References
PubMed ID Title Journal Year
25083866 TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation

Tampé, R, Whiteheart, SW, Florey, O, Blander, JM, Huang, Y, Baccarini, A, Amsen, D, Overholtzer, M, Brown, BD, Seyffer, F, Tung, N, Nair-Gupta, P, Roche, PA, Banerjee, M

Cell 2014
Participants
Input
Output
Participates
as an event of
Orthologous Events
Fusion of ERC and phagosome (Danio rerio)
Fusion of ERC and phagosome (Gallus gallus)
Fusion of ERC and phagosome (Mus musculus)
Fusion of ERC and phagosome (Rattus norvegicus)
Fusion of ERC and phagosome (Sus scrofa)
Fusion of ERC and phagosome (Xenopus tropicalis)
Authored
Garapati, P V  (2016-03-10)
Reviewed
Bergeron, JJ  (2016-05-16)
Created
Garapati, P V  (2016-03-10)
Cite Us!