Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
Stable Identifier
R-HSA-8863731
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
COP9 and TOR1 deneddylate STON2 (Homo sapiens)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol] (Homo sapiens)
NEDD8-STON binds TOR1 hexamer and COP9 complex (Homo sapiens)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
21102408
CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process
Granata, A
,
Warner, TT
,
Schiavo, G
,
Haucke, V
,
Koo, SJ
EMBO J.
2011
Participants
components
COP9 [cytosol]
(Homo sapiens)
NEDD8-STONs [cytosol]
(Homo sapiens)
TOR1 hexamer [cytosol]
(Homo sapiens)
Participates
as an output of
NEDD8-STON binds TOR1 hexamer and COP9 complex (Homo sapiens)
as an input of
COP9 and TOR1 deneddylate STON2 (Homo sapiens)
Inferred To
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Bos taurus)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Caenorhabditis elegans)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Canis familiaris)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Danio rerio)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Dictyostelium discoideum)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Drosophila melanogaster)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Gallus gallus)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Mus musculus)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Rattus norvegicus)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Sus scrofa)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
(Xenopus tropicalis)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text