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AGFG1 [cytosol]
Stable Identifier
R-HSA-8863714
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Arf-GAP domain and FG repeat-containing protein 1, AGFG1_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P42566 EPS15
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
AGFG1 binds VAMP7 (Homo sapiens)
AGFG1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P52594 AGFG1
Gene Names
AGFG1, HRB, RAB, RIP
Chain
chain:1-562
Reference Genes
BioGPS Gene:3267 AGFG1
COSMIC (genes):AGFG1 AGFG1
CTD Gene:3267 AGFG1
dbSNP Gene:3267 AGFG1
ENSEMBL:ENSG00000173744 AGFG1
ENSEMBL_homo_sapiens_GENE:ENSG00000173744.18 AGFG1
HGNC:5175 AGFG1
KEGG Gene (Homo sapiens):3267 AGFG1
Monarch:3267 AGFG1
NCBI Gene:3267 AGFG1
OMIM:600862 AGFG1
UCSC:P52594 AGFG1
Reference Transcript
RefSeq:NM_001135189.1 AGFG1
RefSeq:NM_001135188.1 AGFG1
RefSeq:NM_001135187.1 AGFG1
RefSeq:NM_004504.4 AGFG1
Other Identifiers
11723606_a_at
11723607_a_at
11723608_a_at
11736484_a_at
11740338_a_at
11755694_a_at
16891752
213926_PM_s_at
213926_s_at
218091_PM_at
218091_at
218092_PM_s_at
218092_s_at
226561_PM_at
226561_at
2530600
2530601
2530602
2530605
2530616
2530618
2530619
2530622
2530623
2530625
2530627
2530628
2530629
2530630
2530636
2530639
2530640
2530641
2530642
2530643
2530644
2530645
2530646
2530653
2530654
3267
40579_at
42963_at
66450_at
8048847
90973_at
A_14_P124214
A_14_P135299
A_14_P135304
A_23_P169529
A_33_P3238993
A_33_P3238997
GE57771
GE711776
GO:0001675
GO:0003677
GO:0003723
GO:0005096
GO:0005515
GO:0005634
GO:0005635
GO:0005643
GO:0005737
GO:0005829
GO:0006406
GO:0006913
GO:0007010
GO:0007283
GO:0007289
GO:0022414
GO:0030154
GO:0031410
GO:0043226
GO:0043231
GO:0045109
GO:0046872
GO:0048856
GO:0051028
GO:0098772
HMNXSV003006754
Hs.108082.1.S1_3p_at
Hs.171545.0.A2_3p_at
Hs.171545.1.S1_3p_a_at
ILMN_1792497
ILMN_2196734
L42025_rna1_at
PH_hs_0023955
PH_hs_0040532
TC02001363.hg
g7262381_3p_a_at
Participates
as a component of
AGFG1:VAMP7 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AGFG1:VAMP7 [plasma membrane] (Homo sapiens)
as an input of
AGFG1 binds VAMP7 (Homo sapiens)
Inferred To
Agfg1 [cytosol]
(Mus musculus)
Agfg1 [cytosol]
(Rattus norvegicus)
AGFG1 [cytosol]
(Bos taurus)
AGFG1 [cytosol]
(Canis familiaris)
AGFG1 [cytosol]
(Gallus gallus)
AGFG1 [cytosol]
(Sus scrofa)
drongo [cytosol]
(Drosophila melanogaster)
agfg1 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001128660.1
,
NP_004495.2
,
NP_001128661.1
,
NP_001128659.1
OpenTargets
ENSG00000173744
HPA
ENSG00000173744-AGFG1
GeneCards
P52594
Ensembl
ENSG00000173744
,
ENSP00000362775
,
ENST00000373671
,
ENSP00000387218
,
ENST00000409171
,
ENST00000409979
,
ENST00000310078
,
ENSP00000312059
,
ENSP00000387282
PRO
P52594
Pharos - Targets
P52594
PDB
2VX8
,
2OLM
,
2D9L
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42566 EPS15
2
p-Y849 EPS15 [cytosol]
(R-HSA-8867028)
EPS15 [cytosol]
(R-HSA-182920)
0.656
3
UniProt:P51809 VAMP7
6
VAMP7 [late endosome membrane]
(R-HSA-2193120)
VAMP7 [lysosomal membrane]
(R-HSA-376342)
VAMP7 [plasma membrane]
(R-HSA-376361)
VAMP7 [Golgi membrane]
(R-HSA-266197)
VAMP7 [cytoplasmic vesicle membrane]
(R-HSA-376336)
VAMP7 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869135)
0.639
7
UniProt:P56282 POLE2
1
POLE2 [nucleoplasm]
(R-HSA-68482)
0.556
3
UniProt:Q9P242 NYAP2
0.556
3
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.483
2
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