Reactome | SYTL4 [plasma membrane]

SYTL4 [plasma membrane]

Stable Identifier

R-HSA-8862971

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Synaptotagmin-like protein 4, SYTL4_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96C24 SYTL4

Gene Names

SYTL4

Chain

chain:1-671

Reference Genes

BioGPS Gene:94121 SYTL4

COSMIC (genes):SYTL4 SYTL4

CTD Gene:94121 SYTL4

dbSNP Gene:94121 SYTL4

ENSEMBL:ENSG00000102362 SYTL4

HGNC:15588 SYTL4

Monarch:94121 SYTL4

NCBI Gene:94121 SYTL4

OMIM:300723 SYTL4

UCSC:Q96C24 SYTL4

Reference Transcript

Other Identifiers

11730651_a_at

11730652_a_at

1563513_3p_at

1563513_PM_at

1563513_at

17112623

227703_PM_s_at

227703_s_at

4015437

4015439

4015441

4015442

4015444

4015445

4015446

4015447

4015449

4015450

4015451

4015452

4015453

4015454

4015455

4015456

4015457

4015458

4015459

4015460

4015461

4015462

4015463

4015464

4015465

4015466

4015467

4015468

4015469

4015470

4015473

4015474

58702_at

8173955

94121

A_24_P122337

A_33_P3241651

A_33_P3266730

GE88388

GO:0001778

GO:0005515

GO:0005543

GO:0005768

GO:0005886

GO:0006886

GO:0006887

GO:0008289

GO:0016020

GO:0016192

GO:0030073

GO:0030141

GO:0030658

GO:0031092

GO:0031267

GO:0031410

GO:0032418

GO:0042043

GO:0043226

GO:0045921

GO:0046676

GO:0046872

GO:0050714

GO:0061024

GO:0070382

GO:0071985

GO:1905684

HMNXSV003013649

HMNXSV003042113

Hs.247525.1.A1_3p_a_at

Hs2.376981.1.S1_3p_at

Hs2.376981.1.S1_3p_x_at

ILMN_1719599

PH_hs_0024273

PH_hs_0039973

TC0X001209.hg

Participates

as a member of

Platelet alpha granule membrane components that are released on degranulation [plasma membrane] (Homo sapiens)

Other forms of this molecule

SYTL4 [platelet alpha granule membrane]

Inferred To

sytl4 [plasma membrane] (Danio rerio)

sytl4 [plasma membrane] (Xenopus tropicalis)

SYTL4 [plasma membrane] (Bos taurus)

SYTL4 [plasma membrane] (Canis familiaris)

SYTL4 [plasma membrane] (Dictyostelium discoideum)

SYTL4 [plasma membrane] (Gallus gallus)

SYTL4 [plasma membrane] (Sus scrofa)

btsz [plasma membrane] (Drosophila melanogaster)

Sytl4 [plasma membrane] (Mus musculus)

Sytl4 [plasma membrane] (Rattus norvegicus)

Cross References

ENSEMBL

ENST00000263033, ENSP00000276141, ENST00000685623, ENSP00000362080, ENST00000372981, ENSP00000362072, ENSP00000509693, ENSP00000263033, ENST00000372989, ENST00000276141

OpenTargets

ENSG00000102362

HPA

ENSG00000102362-SYTL4

PRO

Q96C24

Pharos - Targets

Q96C24

PDB

2CSZ, 3FDW, 5X6T

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P51159 RAB27A	5	RAB27A [specific granule lumen] (R-HSA-6799609) RAB27A [extracellular region] (R-HSA-6799682) GGC-RAB27A [melanosome membrane] (R-HSA-8877281) RAB27A [cytosol] (R-HSA-3008674) GGC-RAB27A [cytosol] (R-HSA-8870427)	0.666	5
UniProt:P61764 STXBP1	2	STXBP1 [plasma membrane] (R-HSA-2980862) STXBP1 [cytosol] (R-HSA-6794256)	0.556	3
UniProt:Q86TI0 TBC1D1	2	TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718) p-S237-TBC1D1 [cytosol] (R-HSA-1454673)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:P20336 RAB3A	9	RAB3A [clathrin-sculpted monoamine transport vesicle membrane] (R-HSA-372512) RAB3A [plasma membrane] (R-HSA-210461) RAB3A [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-917743) RAB3A [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-210466) RAB3A [secretory granule membrane] (R-HSA-6804968) RAB3A [clathrin-sculpted acetylcholine transport vesicle membrane] (R-HSA-379365) RAB3A [cytosol] (R-HSA-8870410) GGC-RAB3A [cytosol] (R-HSA-8870429) GGC-RAB3A [secretory granule membrane] (R-HSA-8875319)	0.527	3

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