Reactome | MAGED2 [platelet alpha granule lumen]

MAGED2 [platelet alpha granule lumen]

Stable Identifier

R-HSA-8862956

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

platelet alpha granule lumen

Synonyms

Melanoma-associated antigen D2, MAGD2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UNF1 MAGED2

Gene Names

MAGED2, BCG1

Chain

initiator methionine:, chain:2-606

Reference Genes

BioGPS Gene:10916 MAGED2

COSMIC (genes):MAGED2 MAGED2

CTD Gene:10916 MAGED2

dbSNP Gene:10916 MAGED2

ENSEMBL:ENSG00000102316 MAGED2

ENSEMBL_homo_sapiens_GENE:ENSG00000102316.17 MAGED2

HGNC:16353 MAGED2

KEGG Gene (Homo sapiens):10916 MAGED2

Monarch:10916 MAGED2

NCBI Gene:10916 MAGED2

OMIM:300470 MAGED2

UCSC:Q9UNF1 MAGED2

Reference Transcript

Other Identifiers

10916

11715397_x_at

11748370_a_at

11748489_s_at

11757043_a_at

17104021

208682_3p_s_at

208682_PM_s_at

208682_s_at

213627_PM_at

34859_at

34860_g_at

3978519

3978521

3978522

3978524

3978525

3978526

3978527

3978528

3978529

3978530

3978531

3978532

3978534

3978537

3978539

3978541

3978545

3978549

3978551

3978552

3978553

3978554

3978555

3978557

3978603

51719_at

8167815

A_23_P33894

A_24_P160263

GE60455

GO:0000122

GO:0003014

GO:0005515

GO:0005576

GO:0005634

GO:0005654

GO:0005730

GO:0005829

GO:0006351

GO:0006355

GO:0007565

GO:0016020

GO:0022414

GO:0031093

GO:0031410

GO:0043226

GO:0070294

HMNXSV003001679

Hs.4943.1.A1_3p_s_at

ILMN_1661417

ILMN_1683576

ILMN_1684984

ILMN_1789567

PH_hs_0018327

TC0X000323.hg

TC0X001720.hg

g4732088_3p_a_at

Participates

as a member of

Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)

Other forms of this molecule

MAGED2 [extracellular region]

Inferred To

Maged2 [platelet alpha granule lumen] (Mus musculus)

Maged2 [platelet alpha granule lumen] (Rattus norvegicus)

NSE3 [platelet alpha granule lumen] (Saccharomyces cerevisiae)

MAGED2 [platelet alpha granule lumen] (Bos taurus)

MAGED2 [platelet alpha granule lumen] (Canis familiaris)

MAGED2 [platelet alpha granule lumen] (Dictyostelium discoideum)

ndnl2 [platelet alpha granule lumen] (Danio rerio)

nse3 [platelet alpha granule lumen] (Schizosaccharomyces pombe)

MAGE [platelet alpha granule lumen] (Drosophila melanogaster)

mage [platelet alpha granule lumen] (Gallus gallus)

nsmce3 [platelet alpha granule lumen] (Xenopus tropicalis)

Cross References

RefSeq

NP_803182.1, NP_957516.1, NP_055414.2

OpenTargets

ENSG00000102316

HPA

ENSG00000102316-MAGED2

GeneCards

Q9UNF1

Ensembl

ENST00000375058, ENSP00000218439, ENSP00000379526, ENST00000375053, ENST00000218439, ENSP00000364209, ENST00000375068, ENST00000396224, ENSP00000364198, ENSP00000364193, ENSG00000102316

PRO

Q9UNF1

Pharos - Targets

Q9UNF1

Orphanet

23774

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P52333 JAK3	6	p-Y980 JAK3 [cytosol] (R-HSA-9701438) p-Y904,939-JAK3 [plasma membrane] (R-HSA-8985978) JAK3 [endosome] (R-HSA-8983184) p-JAK3 [cytosol] (R-HSA-8982856) p-Y-JAK3 [cytosol] (R-HSA-9006854) JAK3 [cytosol] (R-HSA-451893)	0.623	4
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.527	5

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