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TOR1A [cytosol]
Stable Identifier
R-HSA-8862858
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Torsin-1A, TOR1A_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
COP9 and TOR1 deneddylate STON2 (Homo sapiens)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol] (Homo sapiens)
TOR1 hexamer [cytosol] (Homo sapiens)
TOR1A hexamer [cytosol] (Homo sapiens)
TOR1A [cytosol] (Homo sapiens)
TOR1 hexamer [cytosol] (Homo sapiens)
TOR1A hexamer [cytosol] (Homo sapiens)
TOR1A [cytosol] (Homo sapiens)
NEDD8-STON binds TOR1 hexamer and COP9 complex (Homo sapiens)
NEDD8-STONs:TOR1 hexamer:COP9 [cytosol] (Homo sapiens)
TOR1 hexamer [cytosol] (Homo sapiens)
TOR1A hexamer [cytosol] (Homo sapiens)
TOR1A [cytosol] (Homo sapiens)
TOR1 hexamer [cytosol] (Homo sapiens)
TOR1A hexamer [cytosol] (Homo sapiens)
TOR1A [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14656 TOR1A
Gene Names
TOR1A, DQ2, DYT1, TA, TORA
Chain
signal peptide:1-20, chain:21-332
Reference Genes
BioGPS Gene:1861 TOR1A
COSMIC (genes):TOR1A TOR1A
CTD Gene:1861 TOR1A
dbSNP Gene:1861 TOR1A
ENSEMBL:ENSG00000136827 TOR1A
HGNC:3098 TOR1A
KEGG Gene (Homo sapiens):1861 TOR1A
Monarch:1861 TOR1A
NCBI Gene:1861 TOR1A
OMIM:605204 TOR1A
UCSC:O14656 TOR1A
Reference Transcript
RefSeq:NM_000113.2 TOR1A
Other Identifiers
0006420390
11720764_a_at
11720765_s_at
11758220_s_at
17099083
1861
202348_3p_s_at
202348_s_at
202349_at
32234_at
3227097
3227099
3227100
3227101
3227102
3227103
3227107
3227108
3227109
3227115
3227116
3227117
3227119
3227120
8164587
A_24_P269687
A_33_P3313889
GE54089
GO:0000166
GO:0000338
GO:0003674
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005635
GO:0005737
GO:0005783
GO:0005788
GO:0005829
GO:0005856
GO:0006457
GO:0006464
GO:0006810
GO:0006950
GO:0006979
GO:0006996
GO:0006998
GO:0007010
GO:0007155
GO:0007267
GO:0008021
GO:0008092
GO:0008150
GO:0009056
GO:0015031
GO:0016020
GO:0016192
GO:0016787
GO:0016887
GO:0019894
GO:0030054
GO:0030133
GO:0030141
GO:0030154
GO:0030426
GO:0030659
GO:0031175
GO:0031410
GO:0031965
GO:0034504
GO:0040011
GO:0042406
GO:0042802
GO:0042995
GO:0043005
GO:0043167
GO:0043226
GO:0043231
GO:0044319
GO:0045104
GO:0045202
GO:0048489
GO:0048856
GO:0048870
GO:0051082
GO:0051085
GO:0051584
GO:0051787
GO:0061024
GO:0061077
GO:0070062
GO:0071712
GO:0071763
GO:0072321
GO:1900244
GO:2000008
ILMN_1805812
PH_hs_0001697
TC09001654.hg
g12653776_3p_a_at
g12653776_3p_x_at
g4557540_3p_at
Participant Of
hasComponent
TOR1A hexamer [cytosol]
Inferred To
Dmel\CG4880 [cytosol] (Drosophila melanogaster)
tor1a [cytosol] (Xenopus tropicalis)
tor1l2 [cytosol] (Danio rerio)
TOR1A [cytosol] (Bos taurus)
TOR1A [cytosol] (Canis familiaris)
TOR1A [cytosol] (Dictyostelium discoideum)
TOR1A [cytosol] (Gallus gallus)
TOR1A [cytosol] (Sus scrofa)
tor-1 [cytosol] (Caenorhabditis elegans)
Homologues of TOR1A [cytosol] (Caenorhabditis elegans)
Homologues of TOR1A [cytosol] (Danio rerio)
Homologues of TOR1A [cytosol] (Drosophila melanogaster)
tor1 [cytosol] (Danio rerio)
tor1l1 [cytosol] (Danio rerio)
tor-2 [cytosol] (Caenorhabditis elegans)
Tor1a [cytosol] (Mus musculus)
Tor1a [cytosol] (Rattus norvegicus)
Torsin [cytosol] (Drosophila melanogaster)
tor1l3 [cytosol] (Danio rerio)
ooc-5 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
NP_000104.1
OpenTargets
ENSG00000136827
HPA
ENSG00000136827-TOR1A
GeneCards
O14656
Ensembl
ENSG00000136827
,
ENSP00000345719
,
ENST00000351698
PRO
O14656
Orphanet
15643
PDB
5J1S
,
6OIF
,
5J1T
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P22692 IGFBP4
5
p-IGFBP4 [endoplasmic reticulum lumen]
(R-HSA-8957038)
IGFBP4 [endoplasmic reticulum lumen]
(R-HSA-8956754)
IGFBP4 [extracellular region]
(R-HSA-381421)
IGFBP4(157-237) [extracellular region]
(R-HSA-381510)
IGFBP4(22-156) [extracellular region]
(R-HSA-381516)
0.556
3
UniProt:P05067 APP
20
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:Q96NW7 LRRC7
3
LRRC7 [specific granule lumen]
(R-HSA-6799616)
LRRC7 [extracellular region]
(R-HSA-6799681)
LRRC7 [cytosol]
(R-HSA-9611351)
0.488
2
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