CCR2, CCR3 bind CCL13

Stable Identifier
R-HSA-8862733
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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CCR2, CCR3 bind CCL13
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C-C motif chemokine 13 (MCP-4, CCL13) is a chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. It signals through the CCR2B and CCR3 receptors.
Literature References
PubMed ID Title Journal Year
12554737 A highly selective CCR2 chemokine agonist encoded by human herpesvirus 6

Schwartz, TW, Lüttichau, HR, Moser, C, Gerstoft, J, Jensen, PØ, Clark-Lewis, I

J. Biol. Chem. 2003
9276730 High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines

Ponath, PD, Baggiolini, M, Dahinden, CA, Rao, P, Rhis, S, Ochensberger, B, Uguccioni, M, LaRosa, GJ, Loetscher, P, Mackay, CR

J. Clin. Invest. 1997
Participants
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Output
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as an event of
Orthologous Events
CCR2, CCR3 bind CCL13 (Gallus gallus)
CCR2, CCR3 bind CCL13 (Mus musculus)
CCR2, CCR3 bind CCL13 (Rattus norvegicus)
Authored
Jupe, S  (2016-03-01)
Reviewed
Jassal, B  (2016-03-01)
Created
Jupe, S  (2016-03-01)
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