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ORAI2
Stable Identifier
R-HSA-8862647
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Protein orai-2, ORAI2_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Platelet calcium homeostasis (Homo sapiens)
Elevation of cytosolic Ca2+ levels (Homo sapiens)
CRAC translocates calcium from the extracellular region to the cytosol (Homo sapiens)
CRAC channel [plasma membrane] (Homo sapiens)
ORAI dimer [plasma membrane] (Homo sapiens)
ORAI2 dimer [plasma membrane] (Homo sapiens)
ORAI2 [plasma membrane] (Homo sapiens)
STIM1 activation of CRAC (Homo sapiens)
CRAC channel [plasma membrane] (Homo sapiens)
ORAI dimer [plasma membrane] (Homo sapiens)
ORAI2 dimer [plasma membrane] (Homo sapiens)
ORAI2 [plasma membrane] (Homo sapiens)
ORAI dimer [plasma membrane] (Homo sapiens)
ORAI2 dimer [plasma membrane] (Homo sapiens)
ORAI2 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)
CRAC translocates calcium from the extracellular region to the cytosol (Homo sapiens)
CRAC channel [plasma membrane] (Homo sapiens)
ORAI dimer [plasma membrane] (Homo sapiens)
ORAI2 dimer [plasma membrane] (Homo sapiens)
ORAI2 [plasma membrane] (Homo sapiens)
STIM1 activation of CRAC (Homo sapiens)
CRAC channel [plasma membrane] (Homo sapiens)
ORAI dimer [plasma membrane] (Homo sapiens)
ORAI2 dimer [plasma membrane] (Homo sapiens)
ORAI2 [plasma membrane] (Homo sapiens)
ORAI dimer [plasma membrane] (Homo sapiens)
ORAI2 dimer [plasma membrane] (Homo sapiens)
ORAI2 [plasma membrane] (Homo sapiens)
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
CRAC translocates calcium from the extracellular region to the cytosol (Homo sapiens)
CRAC channel [plasma membrane] (Homo sapiens)
ORAI dimer [plasma membrane] (Homo sapiens)
ORAI2 dimer [plasma membrane] (Homo sapiens)
ORAI2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96SN7 ORAI2
Gene Names
ORAI2, C7orf19, CBCIP2, TMEM142B, PP1729
Chain
chain:1-254
Reference Genes
BioGPS Gene:80228 ORAI2
COSMIC (genes):ORAI2 ORAI2
CTD Gene:80228 ORAI2
dbSNP Gene:80228 ORAI2
ENSEMBL:ENSG00000160991 ORAI2
HGNC:21667 ORAI2
KEGG Gene (Homo sapiens):hsa:80228 ORAI2
Monarch:80228 ORAI2
NCBI Gene:80228 ORAI2
OMIM:610929 ORAI2
UCSC:Q96SN7 ORAI2
Reference Transcript
RefSeq:NM_001126340.2 ORAI2
RefSeq:NM_032831.3 ORAI2
RefSeq:NM_001271818.1 ORAI2
Other Identifiers
0005550088
0005690139
11732231_a_at
11732232_x_at
11748908_a_at
11755076_x_at
1558426_3p_x_at
1558426_x_at
17049814
217529_at
218811_at
218812_3p_s_at
218812_s_at
231406_at
3016769
3016773
3016774
3016776
3016777
3016778
3016779
3016780
3016781
3016782
3016783
3016784
3016785
3016786
3016787
3016788
40495_at
55137
65937
77619_at
80228
81293_at
8135172
89996_at
91977_s_at
91978_r_at
A_14_P101128
A_14_P131873
A_23_P70915
A_24_P329353
A_24_P337867
CCDS5722
ENSG00000160991
ENSP00000348752
ENSP00000385489
ENSP00000417928
ENSP00000418140
ENSP00000478113
ENST00000356387
ENST00000403646
ENST00000473939
ENST00000478730
ENST00000611770
EntrezGene:80228
g13376752_3p_a_at
g13376752_3p_x_at
GE62643
GE757369
GO:0002115
GO:0005515
GO:0015279
GO:0016020
GO:0016021
GO:0030426
GO:0070588
HGNC:21667
HPA055137
HPA065937
Hs.129568.0.A1_3p_at
Hs.204169.0.A1_3p_at
Hs.289053.0.S1_3p_at
Hs.363308
Hs.736659
MIM:610929
NM_001126340
NM_001271818
NM_001271819
NM_032831
NP_001119812
NP_001258747
NP_001258748
NP_116220
ORAI2
ORAI2-201
ORAI2-202
ORAI2-204
ORAI2-205
ORAI2-210
PF07856
PH_hs_0015028
PH_hs_0033460
PH_hs_0039360
TC07000659.hg
uc003uzj.3
uc003uzk.4
uc031syr.1
uc064gne.1
uc064gng.1
UPI0000070E55
Participant Of
hasComponent
ORAI2 dimer [plasma membrane]
Cross References
RefSeq
NP_001258747.1
,
NP_001119812.1
,
NP_116220.1
GeneCards
Q96SN7
PRO
Q96SN7
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