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HSD17B8 [mitochondrial matrix]
Stable Identifier
R-HSA-8862105
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
Estradiol 17-beta-dehydrogenase 8 ecNumber1.1.1.62/ecNumber, DHB8_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Fatty acyl-CoA biosynthesis (Homo sapiens)
2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Homo sapiens)
2xHSD17B8:2xCBR4 [mitochondrial matrix] (Homo sapiens)
HSD17B8 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92506 HSD17B8
Gene Names
HSD17B8, FABGL, HKE6, RING2, SDR30C1
Chain
chain:1-261
Reference Genes
BioGPS Gene:7923 HSD17B8
COSMIC (genes):HSD17B8 HSD17B8
CTD Gene:7923 HSD17B8
dbSNP Gene:7923 HSD17B8
ENSEMBL:ENSG00000204228 HSD17B8
HGNC:3554 HSD17B8
KEGG:hsa:7923 HSD17B8
Monarch:7923 HSD17B8
NCBI Gene:7923 HSD17B8
OMIM:601417 HSD17B8
UCSC:Q92506 HSD17B8
Reference Transcript
RefSeq:NM_014234.4 HSD17B8
Other Identifiers
11724919_a_at
17007393
17028442
17031254
17033739
17036003
17038722
213540_PM_at
213540_at
2903487
2903489
2903490
2903491
2903492
2903493
2903495
2903497
2903499
2903500
2903501
2903502
2903504
41440_at
7923
8118622
8178234
8179534
A_14_P131137
A_23_P81973
D82061_at
GE79456
GO:0003824
GO:0004303
GO:0005515
GO:0005739
GO:0005740
GO:0005759
GO:0005886
GO:0006629
GO:0006631
GO:0006633
GO:0006694
GO:0006703
GO:0008209
GO:0008210
GO:0016020
GO:0016491
GO:0043226
GO:0047035
GO:0051290
GO:0065003
GO:0070404
GO:0106386
GO:1990204
HMNXSV003014503
Hs.288354.0.S1_3p_at
ILMN_1715324
PH_hs_0025004
PH_hs_0033242
TC06000413.hg
TC6_cox_hap2000103.hg
TC6_dbb_hap3000095.hg
TC6_mann_hap4000087.hg
TC6_mcf_hap5000088.hg
TC6_qbl_hap6000094.hg
Participates
as a component of
2xHSD17B8:2xCBR4 [mitochondrial matrix] (Homo sapiens)
Inferred To
hsd17b8 [mitochondrial matrix]
(Danio rerio)
hsd17b8 [mitochondrial matrix]
(Xenopus tropicalis)
HKE6 [mitochondrial matrix]
(Bos taurus)
HSD17B8 [mitochondrial matrix]
(Canis familiaris)
HSD17B8 [mitochondrial matrix]
(Dictyostelium discoideum)
HSD17B8 [mitochondrial matrix]
(Mus musculus)
HSD17B8 [mitochondrial matrix]
(Plasmodium falciparum)
HSD17B8 [mitochondrial matrix]
(Rattus norvegicus)
HSD17B8 [mitochondrial matrix]
(Saccharomyces cerevisiae)
HSD17B8 [mitochondrial matrix]
(Schizosaccharomyces pombe)
HSD17B8 [mitochondrial matrix]
(Sus scrofa)
Cross References
ENSEMBL
ENSP00000413950
,
ENST00000422433
,
ENSP00000406488
,
ENSP00000230236
,
ENST00000374662
,
ENSP00000387753
,
ENST00000454191
,
ENST00000427295
,
ENSP00000363794
,
ENST00000414463
,
ENST00000230236
,
ENSP00000403538
OpenTargets
ENSG00000204228
HPA
ENSG00000204228-HSD17B8
PRO
Q92506
Pharos - Targets
Q92506
GlyGen
Q92506
HMDB Protein
HMDBP00453
PDB
4CQL
,
4CQM
,
2PD6
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P46199 MTIF2
1
MTIF2 [mitochondrial matrix]
(R-HSA-5368271)
0.527
2
UniProt:Q96EN8 MOCOS
1
PXLP-K264-MOCOS [cytosol]
(R-HSA-947549)
0.527
3
UniProt:P52597 HNRNPF
2
HNRNPF [nucleoplasm]
(R-HSA-71937)
HNRNPF [plasma membrane]
(R-HSA-8950714)
0.527
2
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