FCAMR binds IgA

Stable Identifier
R-HSA-8858428
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
ReviewStatus
5/5
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FCAMR binds IgA
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IgA nephropathy (IgAN), the most common glomerulonephritis, is characterized by the deposition of IgA immune complexes in the glomerular mesangium. This is the result of High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor (FCAMR, CD351) binding to IgA (McDonald et al. 2002).

Literature References
PubMed ID Title Journal Year
11779189 Expression of Fc alpha/mu receptor by human mesangial cells: a candidate receptor for immune complex deposition in IgA nephropathy

Jardine, AG, Cameron, AJ, Allen, JM, McDonald, KJ

Biochem. Biophys. Res. Commun. 2002
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Authored
Garapati, P V  (2016-02-19)
Reviewed
Meldal, BH  (2016-09-14)
Created
Garapati, P V  (2016-02-19)
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