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FTO [nucleoplasm]
Stable Identifier
R-HSA-8857715
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Alpha-ketoglutarate-dependent dioxygenase FTO ecNumber1.14.11.-/ecNumber, FTO_HUMAN
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Damage Reversal (Homo sapiens)
Reversal of alkylation damage by DNA dioxygenases (Homo sapiens)
RNA demethylases demethylate N6-methyladenosine RNA (Homo sapiens)
RNA demethylases [nucleoplasm] (Homo sapiens)
FTO:Fe2+ [nucleoplasm] (Homo sapiens)
FTO [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9C0B1 FTO
Gene Names
FTO, KIAA1752
Chain
chain:1-505
Reference Genes
BioGPS Gene:79068 FTO
COSMIC (genes):FTO FTO
CTD Gene:79068 FTO
dbSNP Gene:79068 FTO
ENSEMBL:ENSG00000140718 FTO
ENSEMBL_homo_sapiens_GENE:ENSG00000140718.22 FTO
HGNC:24678 FTO
KEGG Gene (Homo sapiens):79068 FTO
Monarch:79068 FTO
NCBI Gene:79068 FTO
OMIM:610966 FTO
UCSC:Q9C0B1 FTO
Reference Transcript
RefSeq:NM_001080432.2 FTO
Other Identifiers
11723450_a_at
11723451_x_at
11748888_a_at
16819010
209702_PM_at
209702_at
3661153
3661172
3661173
3661174
3661179
3661184
3661188
3661189
3661190
3661197
3661198
3661203
3661263
3661264
3661265
3661266
3661267
3661268
3661269
3661270
3661271
3661272
3661273
3661274
3661275
3661276
3661277
3661278
37242_at
79068
7995655
A_14_P113865
A_14_P134822
A_23_P113184
A_33_P3350508
GE85781
GO:0001659
GO:0003016
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006281
GO:0006307
GO:0008198
GO:0010883
GO:0016071
GO:0016491
GO:0016607
GO:0016740
GO:0030154
GO:0035515
GO:0035516
GO:0035552
GO:0035553
GO:0040014
GO:0042245
GO:0043226
GO:0043231
GO:0043734
GO:0044065
GO:0046872
GO:0048856
GO:0051213
GO:0060612
GO:0061157
GO:0070350
GO:0070989
GO:0080111
GO:0090335
GO:0140097
GO:0140098
GO:1990931
GO:1990984
HMNXSV003057948
ILMN_1817656
ILMN_2288070
PH_hs_0014754
TC16000449.hg
U79260_at
g1710215_3p_at
Participates
as a component of
FTO:Fe2+ [nucleoplasm] (Homo sapiens)
Inferred To
FTO [nucleoplasm]
(Bos taurus)
FTO [nucleoplasm]
(Canis familiaris)
FTO [nucleoplasm]
(Gallus gallus)
FTO [nucleoplasm]
(Mus musculus)
FTO [nucleoplasm]
(Rattus norvegicus)
FTO [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_001073901.1
OpenTargets
ENSG00000140718
ZINC - Substances
FTO_HUMAN
ZINC target
Q9C0B1
PRO
Q9C0B1
PDB
6AEJ
,
4IE0
,
4CXY
,
4CXX
,
5DAB
,
3LFM
,
5ZMD
,
4IDZ
,
7E8Z
,
4IE6
,
4QHO
,
4ZS3
,
4IE7
,
4IE4
,
6AK4
,
4CXW
,
7CKK
,
4QKN
,
4ZS2
,
7WCV
,
4IE5
,
6AKW
,
5F8P
ZINC - Investigational
FTO_HUMAN
HPA
ENSG00000140718-FTO
GeneCards
Q9C0B1
Ensembl
ENSG00000140718
,
ENSP00000418823
,
ENST00000463855
,
ENSP00000417422
,
ENST00000471389
,
ENST00000431610
,
ENST00000460382
,
ENSP00000417843
,
ENSP00000415636
Pharos - Targets
Q9C0B1
ZINC - Predictions - Purchasable
FTO_HUMAN
Orphanet
18739
HMDB Protein
HMDBP12304
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