Reactome | FTO [nucleoplasm]

Stable Identifier

R-HSA-8857715

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Alpha-ketoglutarate-dependent dioxygenase FTO ecNumber1.14.11.-/ecNumber, FTO_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9C0B1 FTO

Gene Names

FTO, KIAA1752

Chain

chain:1-505

Reference Genes

COSMIC (genes):FTO Q9C0B12

dbSNP Gene:79068 Q9C0B12

ENSEMBL:ENSG00000140718 FTO

Participates

as a component of

Inferred To

FTO [nucleoplasm] (Bos taurus)

FTO [nucleoplasm] (Canis familiaris)

FTO [nucleoplasm] (Gallus gallus)

FTO [nucleoplasm] (Mus musculus)

FTO [nucleoplasm] (Rattus norvegicus)

FTO [nucleoplasm] (Sus scrofa)

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P18827 SDC1	20	HS(4)-SDC1 [plasma membrane] (R-HSA-2076693) HS(6)-SDC1 [plasma membrane] (R-HSA-2076652) HS(2)-SDC1 [plasma membrane] (R-HSA-2076666) HS(1)-SDC1 [plasma membrane] (R-HSA-2076672) HS(3)-SDC1 [plasma membrane] (R-HSA-2076691) HS(5)-SDC1 [plasma membrane] (R-HSA-2076626) SDC1 [plasma membrane] (R-HSA-174758) XylS-SDC1 [Golgi lumen] (R-HSA-2064146) Gal-Xyl-SDC1 [Golgi lumen] (R-HSA-2064148) SDC1 [Golgi lumen] (R-HSA-2054105) Gal-Gal-Xyl-SDC1 [Golgi lumen] (R-HSA-2064247) GlcA-Gal-Gal-Xyl-SDC1 [Golgi lumen] (R-HSA-2064082) HS(3)-SDC1 [Golgi lumen] (R-HSA-2076444) HS(4)-SDC1 [Golgi lumen] (R-HSA-2076593) HS(2)-SDC1 [Golgi lumen] (R-HSA-2076309) HS(1)-SDC1 [Golgi lumen] (R-HSA-2076321) Heparan(4)-SDC1 [Golgi lumen] (R-HSA-2076339) Heparan(3)-SDC1 [Golgi lumen] (R-HSA-2076314) Heparan(2)-SDC1 [Golgi lumen] (R-HSA-2076558) Heparan(1)-SDC1 [Golgi lumen] (R-HSA-2076349)	0.527	2
UniProt:O95076 ALX3	1	ALX3 [nucleoplasm] (R-HSA-9858233)	0.527	2
UniProt:P02675 FGB	5	FGB [extracellular region] (R-HSA-140584) FGB(31-44) [extracellular region] (R-HSA-140876) FGB [plasma membrane] (R-HSA-140917) FGB(31-491) [extracellular region] (R-HSA-140846) FGB(31-491) [platelet alpha granule lumen] (R-HSA-140921)	0.527	2
UniProt:Q6IPR3 TYW3	1	TYW3 [cytoplasm] (R-HSA-6782888)	0.527	2

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