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Golgi-to-ER retrograde transport
Stable Identifier
R-HSA-8856688
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Golgi-to-ER retrograde transport (Homo sapiens)
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Retrograde traffic from the cis-Golgi to the ERGIC or the ER occurs through either COPI-coated vesicles or through a less well characterized RAB6-dependent route that makes use of tubular carriers (reviewed in Lord et al, 2013; Spang et al, 2013; Heffernan and Simpson, 2014). The balance between these two pathways may be influenced cargo type and concentration and membrane composition, though the details remain to be worked out (reviewed in Heffernan and Simpson, 2014).
Literature References
PubMed ID
Title
Journal
Year
23732476
Retrograde traffic from the Golgi to the endoplasmic reticulum
Spang, A
Cold Spring Harb Perspect Biol
2013
23378591
The highly conserved COPII coat complex sorts cargo from the endoplasmic reticulum and targets it to the golgi
Ferro-Novick, S
,
Miller, EA
,
Lord, C
Cold Spring Harb Perspect Biol
2013
25233431
The trials and tubule-ations of Rab6 involvement in Golgi-to-ER retrograde transport
Simpson, JC
,
Heffernan, LF
Biochem. Soc. Trans.
2014
Participants
Events
COPI-dependent Golgi-to-ER retrograde traffic
(Homo sapiens)
COPI-independent Golgi-to-ER retrograde traffic
(Homo sapiens)
Participates
as an event of
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Orthologous Events
Golgi-to-ER retrograde transport (Bos taurus)
Golgi-to-ER retrograde transport (Caenorhabditis elegans)
Golgi-to-ER retrograde transport (Canis familiaris)
Golgi-to-ER retrograde transport (Danio rerio)
Golgi-to-ER retrograde transport (Dictyostelium discoideum)
Golgi-to-ER retrograde transport (Drosophila melanogaster)
Golgi-to-ER retrograde transport (Gallus gallus)
Golgi-to-ER retrograde transport (Mus musculus)
Golgi-to-ER retrograde transport (Plasmodium falciparum)
Golgi-to-ER retrograde transport (Rattus norvegicus)
Golgi-to-ER retrograde transport (Saccharomyces cerevisiae)
Golgi-to-ER retrograde transport (Schizosaccharomyces pombe)
Golgi-to-ER retrograde transport (Sus scrofa)
Golgi-to-ER retrograde transport (Xenopus tropicalis)
Authored
Rothfels, K (2016-01-06)
Reviewed
Gillespie, ME (2016-02-02)
Created
Rothfels, K (2016-02-12)
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