Reactome | CIDEC [cytosol]

CIDEC [cytosol]

Stable Identifier

R-HSA-8856627

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Cell death activator CIDE-3, CIDEC_HUMAN

Locations in the PathwayBrowser

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Gene expression (Transcription) (Homo sapiens)

- Epigenetic regulation of gene expression (Homo sapiens)
  - Epigenetic regulation by WDR5-containing histone modifying complexes (Homo sapiens)
    - Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Homo sapiens)
      - Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Homo sapiens)
        
        MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Homo sapiens)
        
        CIDEC gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
        
        CIDEC [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96AQ7 CIDEC

Gene Names

CIDEC, FSP27

Chain

chain:1-238

Reference Genes

BioGPS Gene:63924 CIDEC

COSMIC (genes):CIDEC CIDEC

CTD Gene:63924 CIDEC

dbSNP Gene:63924 CIDEC

ENSEMBL:ENSG00000187288 CIDEC

HGNC:24229 CIDEC

KEGG:hsa:63924 CIDEC

Monarch:63924 CIDEC

NCBI Gene:63924 CIDEC

OMIM:612120 CIDEC

UCSC:Q96AQ7 CIDEC

Reference Transcript

Participates

as a component of

CIDEA:CIDEC [cytosol] (Homo sapiens)

as an output of

CIDEC gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)

Inferred To

Drep3 [cytosol] (Drosophila melanogaster)

Cidec [cytosol] (Mus musculus)

Cidec [cytosol] (Rattus norvegicus)

CIDEC [cytosol] (Bos taurus)

CIDEC [cytosol] (Canis familiaris)

CIDEC [cytosol] (Gallus gallus)

cidec [cytosol] (Danio rerio)

cidec [cytosol] (Xenopus tropicalis)

Drep1 [cytosol] (Drosophila melanogaster)

Homologues of CIDEC [cytosol] (Drosophila melanogaster)

CIDE-C [cytosol] (Sus scrofa)

Drep2 [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_001365420.1, NP_001308073.1, NP_001186481.1, NP_001308071.1, NP_001186480.1, XP_054203465.1, XP_047304642.1, NP_001308072.1, NP_001186552.1, XP_047304641.1, NP_071377.2

OpenTargets

ENSG00000187288

ENSEMBL

ENSP00000483641, ENST00000679265, ENSP00000400649, ENSP00000504614, ENSP00000502377, ENST00000423850, ENST00000336832, ENSG00000187288, ENSP00000392975, ENST00000618572, ENST00000675828, ENSP00000338642, ENST00000455015, ENST00000430427, ENSP00000408631

HPA

ENSG00000187288-CIDEC

GeneCards

CIDEC

PRO

Q96AQ7

Pharos - Targets

Q96AQ7

Orphanet

CIDEC

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:A6NJ78-4 METTL15			0.556	3
UniProt:Q6NVU6 UFSP1			0.556	3
UniProt:Q15466 NR0B2	1	NR0B2 [nucleoplasm] (R-HSA-376312)	0.556	3
UniProt:Q9BS75 Q9BS75			0.556	3
UniProt:B2RXF5 ZBT42			0.556	3
UniProt:Q7Z6I5 SPT12			0.556	3

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