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Sda-UMOD [Golgi lumen]
Stable Identifier
R-HSA-8855988
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Uromodulin, UROM_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD (Homo sapiens)
Sda-UMOD [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P07911 UMOD
Gene Names
UMOD
Chain
signal peptide:1-24, chain:25-614, chain:25-587, propeptide:615-640
Reference Genes
BioGPS Gene:7369 UMOD
COSMIC (genes):UMOD UMOD
CTD Gene:7369 UMOD
dbSNP Gene:7369 UMOD
ENSEMBL:ENSG00000169344 UMOD
HGNC:12559 UMOD
KEGG:hsa:7369 UMOD
Monarch:7369 UMOD
NCBI Gene:7369 UMOD
OMIM:191845 UMOD
UCSC:P07911 UMOD
Reference Transcript
RefSeq:NM_001278614.1 UMOD
RefSeq:NM_001008389.2 UMOD
RefSeq:NM_003361.3 UMOD
Other Identifiers
11733775_a_at
16824602
16824620
206716_PM_at
206716_at
3683550
3683551
3683553
3683554
3683555
3683557
3683558
3683560
3683563
3683564
3683565
3683566
3683567
3683568
3683569
3683570
3683571
3683572
3683573
3683574
3683575
3683576
3683577
3683578
3683579
3683580
3683582
3683583
37452_at
7369
77688_at
7999936
80094_at
A_23_P158775
GE81269
GO:0000922
GO:0001822
GO:0002251
GO:0002376
GO:0003014
GO:0003091
GO:0003094
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005783
GO:0005796
GO:0005886
GO:0005929
GO:0006457
GO:0006629
GO:0006874
GO:0006883
GO:0006886
GO:0006914
GO:0006915
GO:0006954
GO:0006968
GO:0006986
GO:0007029
GO:0007155
GO:0007157
GO:0007159
GO:0008217
GO:0008285
GO:0008380
GO:0009410
GO:0009414
GO:0009986
GO:0010467
GO:0012501
GO:0015747
GO:0016020
GO:0016323
GO:0016324
GO:0019864
GO:0019898
GO:0030163
GO:0030643
GO:0030644
GO:0032496
GO:0033209
GO:0033555
GO:0034620
GO:0034976
GO:0035809
GO:0036503
GO:0042995
GO:0043226
GO:0044861
GO:0045087
GO:0046720
GO:0048856
GO:0048870
GO:0048871
GO:0048878
GO:0050801
GO:0050829
GO:0050891
GO:0051223
GO:0055062
GO:0055064
GO:0055074
GO:0055075
GO:0055078
GO:0055085
GO:0060073
GO:0060170
GO:0061024
GO:0061077
GO:0070062
GO:0070294
GO:0071918
GO:0072044
GO:0072051
GO:0072070
GO:0072218
GO:0072221
GO:0072233
GO:0072665
GO:0097190
GO:0097709
GO:0097744
GO:0098542
GO:0098552
GO:0140367
GO:1990266
HMNXSV003049895
HMNXSV003050560
ILMN_1740585
ILMN_2406151
M15881_at
PH_hs_0031697
TC16000924.hg
TC16001796.hg
g4507832_3p_at
Participates
as an output of
B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD (Homo sapiens)
Other forms of this molecule
UMOD [Golgi lumen]
Inferred To
Homologues of Sda-UMOD [Golgi lumen]
(Danio rerio)
UMOD [Golgi lumen]
(Bos taurus)
UMOD [Golgi lumen]
(Canis familiaris)
UMOD [Golgi lumen]
(Sus scrofa)
Sda-UMOD [Golgi lumen]
(Danio rerio)
si:dkey-239b22.2 [Golgi lumen]
(Danio rerio)
Umod [Golgi lumen]
(Mus musculus)
Umod [Golgi lumen]
(Rattus norvegicus)
umod.3 [Golgi lumen]
(Xenopus tropicalis)
Modified Residues
Name
galactosylated residue (GalNAc-beta1-4(Neu5Ac-alpha2-3)Gal-beta1-4GlcNAc-beta1-3Gal-R group) at unknown position
Modification
GalNAc-beta1-4(Neu5Ac-alpha2-3)Gal-beta1-4GlcNAc-beta1-3Gal-R group
PsiMod Name
galactosylated residue
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with an galactose group through a glycosidic bond.
Cross References
ENSEMBL
ENST00000396138
,
ENSP00000379442
,
ENSP00000379438
,
ENSG00000169344
,
ENST00000570689
,
ENST00000396134
,
ENSP00000460548
OpenTargets
ENSG00000169344
GeneCards
UMOD
HPA
ENSG00000169344-UMOD
PRO
P07911
Pharos - Targets
P07911
GlyGen
P07911
Orphanet
UMOD
PDB
6ZYA
,
7Q3N
,
6ZS5
,
6TQL
,
6TQK
,
7PFP
,
4WRN
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BWP8-PRO_0000315044 COLEC11
0.558
2
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