ARTN binds RET:GFRA1,GFRA3

Stable Identifier
R-HSA-8853800
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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ARTN binds RET:GFRA1,GFRA3
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Artemin (ARTN) is a ligand for GDNF family receptor-alpha (GFRA) 1 and 3, preferentially binding GFRA3 (Baloh et al. 1998).
Literature References
PubMed ID Title Journal Year
9883723 Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex

Enomoto, H, Lampe, PA, Simburger, KS, Johnson, EM, Milbrandt, J, Fahrner, TJ, Tansey, MG, Baloh, RH, Araki, T, Leitner, ML

Neuron 1998
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Orthologous Events
ARTN binds RET:GFRA1,GFRA3 (Bos taurus)
ARTN binds RET:GFRA1,GFRA3 (Gallus gallus)
ARTN binds RET:GFRA1,GFRA3 (Mus musculus)
ARTN binds RET:GFRA1,GFRA3 (Rattus norvegicus)
ARTN binds RET:GFRA1,GFRA3 (Sus scrofa)
Authored
Jupe, S  (2016-01-25)
Reviewed
Luo, W  (2016-05-17)
Morales, D  (2016-05-06)
Created
Jupe, S  (2016-01-25)
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