2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1

Stable Identifier
R-HSA-8853755
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Phosphorylated RET binds Phospholipase C gamma 1 (PLCG1) via tyrosine 905 (Borello et al. 1996) and/or tyrosine-1015 (Lundgren et al. 2012).

Literature References
PubMed ID Title Journal Year
8628282 The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma

Borrello, MG, Alberti, L, Arighi, E, Bongarzone, I, Battistini, C, Bardelli, A, Pasini, B, Piutti, C, Rizzetti, MG, Mondellini, P, Radice, MT, Pierotti, MA

Mol. Cell. Biol. 1996
Participants
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Orthologous Events
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