Reactome | GTSE1 binds PLK1

GTSE1 binds PLK1

Stable Identifier

R-HSA-8852324

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

GTSE1 binds PLK1. The two proteins co-localize on centrosomes from G2 phase to prophase, but not after metaphase (Liu et al. 2010).

Literature References

PubMed ID	Title	Journal	Year
20577264	Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery Liu, XS, Li, H, Song, B, Liu, X	EMBO Rep.	2010

Participants

Input

Output

GTSE1:p-T210-PLK1 [cytosol] (Homo sapiens)

Participant Of

hasEvent

The role of GTSE1 in G2/M progression after G2 checkpoint

Orthologous Events

GTSE1 binds PLK1 (Bos taurus)

GTSE1 binds PLK1 (Canis familiaris)

GTSE1 binds PLK1 (Danio rerio)

GTSE1 binds PLK1 (Gallus gallus)

GTSE1 binds PLK1 (Mus musculus)

GTSE1 binds PLK1 (Rattus norvegicus)

GTSE1 binds PLK1 (Sus scrofa)

GTSE1 binds PLK1 (Xenopus tropicalis)

Authored

Orlic-Milacic, M (2016-01-15)

Reviewed

Bird, AW (2016-01-22)

Created

Orlic-Milacic, M (2016-01-15)