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GTSE1 [cytosol]
Stable Identifier
R-HSA-8852264
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
G2 and S phase-expressed protein 1, Protein B99 homolog
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
The role of GTSE1 in G2/M progression after G2 checkpoint (Homo sapiens)
GTSE1 binds CDKN1A (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
GTSE1:CDKN1A:FKBPL:HSP90 [cytosol] (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
GTSE1 binds PLK1 (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
GTSE1:p-T210-PLK1 [cytosol] (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
GTSE1 binds microtubule lattice in interphase cells (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
GTSE1:microtubule [cytosol] (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Homo sapiens)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
PLK1 phosphorylates GTSE1 (Homo sapiens)
GTSE1:p-T210-PLK1 [cytosol] (Homo sapiens)
GTSE1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYZ3 GTSE1
Gene Names
GTSE1
Chain
chain:1-739
Reference Genes
BioGPS Gene:51512 GTSE1
COSMIC (genes):GTSE1 GTSE1
CTD Gene:51512 GTSE1
dbSNP Gene:51512 GTSE1
ENSEMBL:ENSG00000075218 GTSE1
HGNC:13698 GTSE1
KEGG:hsa:51512 GTSE1
Monarch:51512 GTSE1
NCBI Gene:51512 GTSE1
OMIM:607477 GTSE1
UCSC:Q9NYZ3 GTSE1
Reference Transcript
RefSeq:NM_016426.6 GTSE1
RefSeq:XM_017028815.1 GTSE1
RefSeq:XM_005261627.3 GTSE1
Other Identifiers
11736082_a_at
11736083_x_at
16931384
204315_PM_s_at
204315_s_at
204318_PM_s_at
204318_s_at
211040_PM_x_at
211040_x_at
215942_PM_s_at
215942_s_at
39374_at
39375_g_at
3949056
3949059
3949061
3949062
3949063
3949064
3949067
3949068
3949070
3949078
3949080
3949081
3949082
3949083
3949084
3949085
3949086
3949087
3949088
3949089
3949090
3949091
39872_at
51512
63703_s_at
8073858
A_14_P135311
A_23_P57588
GE82125
GO:0003674
GO:0005515
GO:0005654
GO:0005737
GO:0005829
GO:0005856
GO:0005874
GO:0005881
GO:0006977
GO:0007017
GO:0008017
GO:0008092
GO:0015630
GO:0016020
GO:0043226
HMNXSV003027674
Hs.122552.0.S1_3p_s_at
Hs.122552.2.S1_3p_s_at
TC22000394.hg
g13623450_3p_s_at
p33936
Participates
as a component of
GTSE1:microtubule [cytosol] (Homo sapiens)
GTSE1:CDKN1A:FKBPL:HSP90 [cytosol] (Homo sapiens)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Homo sapiens)
GTSE1:p-T210-PLK1 [cytosol] (Homo sapiens)
as an input of
GTSE1 binds microtubule lattice in interphase cells (Homo sapiens)
GTSE1 binds CDKN1A (Homo sapiens)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Homo sapiens)
GTSE1 binds PLK1 (Homo sapiens)
Other forms of this molecule
p-S435-GTSE1 [cytosol]
p-S435-GTSE1 [nucleoplasm]
p-T513,T526-GTSE1 [cytosol]
Inferred To
gtse1 [cytosol]
(Danio rerio)
gtse1 [cytosol]
(Xenopus tropicalis)
GTSE1 [cytosol]
(Bos taurus)
GTSE1 [cytosol]
(Canis familiaris)
GTSE1 [cytosol]
(Gallus gallus)
GTSE1 [cytosol]
(Sus scrofa)
Gtse1 [cytosol]
(Mus musculus)
Gtse1 [cytosol]
(Rattus norvegicus)
Ghost homologue of GTSE1 [cytosol]
(Dictyostelium discoideum)
Ghost homologue of GTSE1 [cytosol]
(Plasmodium falciparum)
Cross References
RefSeq
XP_016884304.1
,
XP_005261684.1
,
NP_057510.4
OpenTargets
ENSG00000075218
ENSEMBL
ENSP00000415430
,
ENST00000454366
HPA
ENSG00000075218-GTSE1
PRO
Q9NYZ3
Pharos - Targets
Q9NYZ3
GlyGen
Q9NYZ3
PDB
6QNP
,
6QNN
Interactors (16)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q709F0 ACAD11
1
ACAD11 [mitochondrial inner membrane]
(R-HSA-5695987)
0.643
3
UniProt:Q96FJ0 STAMBPL1
1
STAMBPL1 [cytosol]
(R-HSA-6783264)
0.643
3
UniProt:O95630 STAMBP
1
STAMBP [cytosol]
(R-HSA-5693063)
0.643
3
UniProt:P53350 PLK1
4
PLK1 [cytosol]
(R-HSA-164603)
p-T210-PLK1 [nucleoplasm]
(R-HSA-3002800)
p-T210-PLK1 [cytosol]
(R-HSA-3000318)
PLK1 [nucleoplasm]
(R-HSA-156720)
0.571
6
UniProt:Q00610 CLTC
10
CLTC [trans-Golgi network membrane]
(R-HSA-5333703)
CLTC [cytosol]
(R-HSA-8856820)
CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-ALK(1058-1620) fusion [cytosol]
(R-HSA-9710852)
CLTC(2-1634)insV-p-7Y-ALK(1059-1620) fusion [cytosol]
(R-HSA-9710854)
CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9710835)
CLTC(2-1634)insV-ALK(1059-1620) fusion [cytosol]
(R-HSA-9710853)
CLTC [endolysosome membrane]
(R-HSA-8870827)
CLTC [clathrin-coated endocytic vesicle membrane]
(R-HSA-5138450)
CLTC [lysosomal membrane]
(R-HSA-2980660)
CLTC [plasma membrane]
(R-HSA-2980668)
0.564
3
UniProt:Q9UJY5 GGA1
2
GGA1 [early endosome membrane]
(R-HSA-8854136)
GGA1 [endosome membrane]
(R-HSA-5692930)
0.544
2
UniProt:Q8WTP9 XAGE3
0.527
2
UniProt:Q13492-2 PICALM
0.527
2
UniProt:Q9Y664 KPTN
1
KPTN [lysosomal membrane]
(R-HSA-9638238)
0.527
2
UniProt:Q06190 P2R3A
0.527
2
UniProt:Q5SZD1 CF141
0.527
2
UniProt:P01350 GAST
1
GAST(76-92) [extracellular region]
(R-HSA-870266)
0.527
2
UniProt:P56539 CAV3
1
CAV3 [plasma membrane]
(R-HSA-1368135)
0.527
2
UniProt:Q13492 PICALM
3
PICALM [Golgi membrane]
(R-HSA-434341)
PICALM [cytoplasmic vesicle membrane]
(R-HSA-429812)
PICALM [cytosol]
(R-HSA-8867593)
0.527
2
UniProt:Q92466 DDB2
3
DDB2 [nucleoplasm]
(R-HSA-53491)
PAR-DDB2 [nucleoplasm]
(R-HSA-5696654)
PolyUb-DDB2 [nucleoplasm]
(R-HSA-6783035)
0.527
2
UniProt:Q01968 OCRL
4
OCRL [Golgi membrane]
(R-HSA-434339)
OCRL [cytoplasmic vesicle membrane]
(R-HSA-434214)
OCRL [plasma membrane]
(R-HSA-3769049)
OCRL [cytosol]
(R-HSA-1806196)
0.527
2
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