Reactome | ALYREF, FYTTD1, LUZP4 [nucleoplasm]

ALYREF, FYTTD1, LUZP4

Stable Identifier

R-HSA-8852182

Type

Set [CandidateSet]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - RNA Polymerase II Transcription Termination (Homo sapiens)
    - Cleavage of Growing Transcript in the Termination Region (Homo sapiens)
      - Cleavage of mRNA at the 3'-end (Homo sapiens)
        
        3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Homo sapiens)
        
        ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Homo sapiens)
        
        Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Homo sapiens)
        
        ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
25662211	Luzp4 defines a new mRNA export pathway in cancer cells Viphakone, N, Cumberbatch, MG, Livingstone, MJ, Heath, PR, Dickman, MJ, Catto, JW, Wilson, SA	Nucleic Acids Res.	2015
19836239	UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA Hautbergue, GM, Hung, ML, Walsh, MJ, Snijders, AP, Chang, CT, Jones, R, Ponting, CP, Dickman, MJ, Wilson, SA	Curr. Biol.	2009

Participants

members

ALYREF [nucleoplasm] (Homo sapiens)

candidates

Participant Of

input

TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally

output

Docking of the TAP:EJC Complex with the NPC

hasComponent

Inferred To

Ghost homologue of ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Arabidopsis thaliana)

Ghost homologue of ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Danio rerio)

Ghost homologue of ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Oryza sativa)

ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Bos taurus)

ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Canis familiaris)

ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Gallus gallus)

ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Mus musculus)

ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Rattus norvegicus)

ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Sus scrofa)

ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Taeniopygia guttata)

ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Xenopus tropicalis)

© 2018 Reactome