BTNL8 binds resting T cell surface

Stable Identifier
R-HSA-8852013
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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BTNL8 binds resting T cell surface
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Human BTNL8 (butyrophilin like 8), shares characteristics of both B7 and BTN like (BTNL) proteins. BTNL8 was shown to interact with a putative receptor on the surface of resting T cells but not activated T cells, and is able to promote activation of resting T lymphocytes (Chapoval et al. 2013).
Literature References
PubMed ID Title Journal Year
24036152 BTNL8, a butyrophilin-like molecule that costimulates the primary immune response

Andrew, D, Mesri, M, Feshchenko, EA, Khramtsov, NV, Mezes, PS, Boldog, FL, Brunick, L, Starling, GC, Chapoval, AI, Smithson, G

Mol. Immunol. 2013
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Orthologous Events
BTNL8 binds resting T cell surface (Gallus gallus)
BTNL8 binds resting T cell surface (Xenopus tropicalis)
Authored
Garapati, P V  (2016-01-05)
Reviewed
Reith, W  (2016-09-09)
Rhodes, DA  (2017-03-01)
Created
Garapati, P V  (2016-01-12)
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