BTNL8 binds resting T cell surface

Stable Identifier
R-HSA-8852013
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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BTNL8 binds resting T cell surface
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Human BTNL8 (butyrophilin like 8), shares characteristics of both B7 and BTN like (BTNL) proteins. BTNL8 was shown to interact with a putative receptor on the surface of resting T cells but not activated T cells, and is able to promote activation of resting T lymphocytes (Chapoval et al. 2013).
Literature References
PubMed ID Title Journal Year
24036152 BTNL8, a butyrophilin-like molecule that costimulates the primary immune response

Chapoval, AI, Smithson, G, Brunick, L, Mesri, M, Boldog, FL, Andrew, D, Khramtsov, NV, Feshchenko, EA, Starling, GC, Mezes, PS

Mol. Immunol. 2013
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Orthologous Events
BTNL8 binds resting T cell surface (Gallus gallus)
Authored
Garapati, P V  (2016-01-05)
Reviewed
Reith, W  (2016-09-09)
Rhodes, DA  (2017-03-01)
Created
Garapati, P V  (2016-01-12)
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