GPR183 [plasma membrane]

Stable Identifier
R-HSA-8851676
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
G-protein coupled receptor 183, GP183_HUMAN
Locations in the PathwayBrowser
Expand all
General

GPR183 (originally called EBI2) binds the oxysterol 7alpha,25-dihydroxycholesterol (7a,25-OHC) (Hannedouche et al. 2011, Liu et al. 2011). GPR183 is believed to played a key role in regulating B cell migration and responses (Gatto et al. 2009, Pereira et al. 2009, Yi et al. 2012, Sun & Liu 2015). It signals via Gi (Rosenkilde et al. 2006).

External Reference Information
External Reference
UniProt:P32249 GPR183
Gene Names
GPR183, EBI2
Chain
chain:1-361
Reference Genes
BioGPS Gene:1880 GPR183
COSMIC (genes):GPR183 GPR183
CTD Gene:1880 GPR183
dbSNP Gene:1880 GPR183
ENSEMBL:ENSG00000169508 GPR183
ENSEMBL_homo_sapiens_GENE:ENSG00000169508 GPR183
HGNC:3128 GPR183
KEGG Gene (Homo sapiens):1880 GPR183
Monarch:1880 GPR183
NCBI Gene:1880 GPR183
OMIM:605741 GPR183
UCSC:P32249 GPR183
Reference Transcript
Other Identifiers
0000070341
11727428_at
11758555_s_at
16780592
1880
205419_at
28847
33690
3522663
3522664
3522665
3522669
7972557
931_at
A0A024RDX2
A_23_P25566
AAA35924
AAH20752
AK223390
AK292091
AK313443
AL160155
BAD97110
BAF84780
BAG36232
BC020752
CAB033690
CCDS9492
CH471085
EAX09018
EAX09019
ENSG00000169508
ENSP00000365596
ENST00000376414
ENST00000376414.4
EntrezGene:1880
g4826705_3p_at
g4826705_3p_x_at
GE57589
GO:0002250
GO:0002313
GO:0002376
GO:0002407
GO:0003674
GO:0004930
GO:0005575
GO:0005886
GO:0005887
GO:0006955
GO:0006959
GO:0007165
GO:0007186
GO:0008142
GO:0008150
GO:0008289
GO:0010818
GO:0016020
GO:0016021
GO:0030154
GO:0030316
GO:0030595
GO:0030890
GO:0036145
GO:0040011
GO:0042592
GO:0048870
GO:0060326
GO:0061470
GO:0070374
GO:2000458
GPR183
GPR183-201
HGNC:3128
HPA028847
ILMN_1798706
ILMN_2168217
ILMN_3235514
IPR000276
IPR017452
L08177
L08177_at
MIM:605741
NM_004951
NP_004942
PF00001
PH_hs_0000092
PH_hs_0040414
PR00237
PR01157
SM01381
TC13000829.hg
UPI0000001068
XM_017020405
XP_016875894
Participant Of
input
hasMember
hasComponent
Inferred To
GPR183 [plasma membrane] (Bos taurus)
GPR183 [plasma membrane] (Canis familiaris)
GPR183 [plasma membrane] (Danio rerio)
GPR183 [plasma membrane] (Gallus gallus)
GPR183 [plasma membrane] (Mus musculus)
GPR183 [plasma membrane] (Rattus norvegicus)
GPR183 [plasma membrane] (Sus scrofa)
GPR183 [plasma membrane] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
ZINC - Substances
GeneCards
ZINC target
PRO
ZINC - Predictions - Purchasable