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HERC3 [cytosol]
Stable Identifier
R-HSA-8851651
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Probable E3 ubiquitin-protein ligase HERC3 ecNumber6.3.2.-/ecNumber, HERC3_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
HERC3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15034 HERC3
Gene Names
HERC3, KIAA0032
Chain
chain:1-1050
Reference Genes
BioGPS Gene:8916 HERC3
COSMIC (genes):HERC3 HERC3
CTD Gene:8916 HERC3
dbSNP Gene:8916 HERC3
ENSEMBL:ENSG00000138641 HERC3
ENSEMBL_homo_sapiens_GENE:ENSG00000138641.18 HERC3
HGNC:4876 HERC3
KEGG Gene (Homo sapiens):8916 HERC3
Monarch:8916 HERC3
NCBI Gene:8916 HERC3
OMIM:605200 HERC3
UCSC:Q15034 HERC3
Reference Transcript
RefSeq:NM_014606.2 HERC3
RefSeq:NM_001271602.1 HERC3
RefSeq:XM_005263327.3 HERC3
RefSeq:NM_001318505.1 HERC3
Other Identifiers
11725406_a_at
11725407_s_at
11761495_at
1554290_PM_at
1554290_at
16968797
206183_PM_s_at
206183_s_at
2735461
2735463
2735466
2735467
2735482
2735483
2735485
2735486
2735487
2735488
2735489
2735490
2735491
2735492
2735494
2735495
2735497
2735499
2735500
2735503
2735504
2735506
2735507
2735508
2735509
2735510
2735512
2735514
2735523
2735524
2735526
2735528
2735529
2735530
2735532
2735534
35689_at
63102_at
8096385
8916
A_14_P104776
A_14_P135653
A_23_P121586
A_24_P51201
D25215_at
GE57120
GO:0003824
GO:0004842
GO:0005737
GO:0006511
GO:0016567
GO:0016740
GO:0030163
GO:0031410
GO:0036211
GO:0043226
GO:0061630
GO:0140096
HMNXSV003006050
HMNXSV003010250
Hs2.422481.1.S1_3p_at
ILMN_1741032
PH_hs_0002879
TC04000486.hg
g7657151_3p_a_at
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
Herc3 [cytosol]
(Mus musculus)
Herc3 [cytosol]
(Rattus norvegicus)
Homologues of HERC3 [cytosol]
(Caenorhabditis elegans)
Homologues of HERC3 [cytosol]
(Dictyostelium discoideum)
HERC3 [cytosol]
(Bos taurus)
HERC3 [cytosol]
(Canis familiaris)
HERC3 [cytosol]
(Dictyostelium discoideum)
HERC3 [cytosol]
(Gallus gallus)
HERC3 [cytosol]
(Plasmodium falciparum)
HERC3 [cytosol]
(Sus scrofa)
herc-1 [cytosol]
(Caenorhabditis elegans)
herc3 [cytosol]
(Xenopus tropicalis)
gacGG [cytosol]
(Dictyostelium discoideum)
glo-4 [cytosol]
(Caenorhabditis elegans)
tirA [cytosol]
(Dictyostelium discoideum)
Herc4 [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
XP_005263384.1
,
NP_001305434.1
,
NP_001258531.1
,
NP_055421.1
OpenTargets
ENSG00000138641
HPA
ENSG00000138641-HERC3
GeneCards
Q15034
Ensembl
ENST00000264345
,
ENSP00000385684
,
ENSP00000264345
,
ENST00000402738
,
ENST00000407637
,
ENSP00000384005
,
ENSG00000138641
PRO
Q15034
Pharos - Targets
Q15034
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