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ZNF645 [cytosol]
Stable Identifier
R-HSA-8851646
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase ZNF645 ecNumber6.3.2.-/ecNumber, ZN645_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
ZNF645 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N7E2 CBLL2
Gene Names
CBLL2, ZNF645
Chain
chain:1-425
Reference Genes
BioGPS Gene:158506 CBLL2
COSMIC (genes):CBLL2 CBLL2
CTD Gene:158506 CBLL2
dbSNP Gene:158506 CBLL2
ENSEMBL:ENSG00000175809 ZNF645
ENSEMBL_homo_sapiens_GENE:ENSG00000175809.6 CBLL2
HGNC:26371 CBLL2
KEGG Gene (Homo sapiens):158506 CBLL2
Monarch:158506 CBLL2
NCBI Gene:158506 CBLL2
UCSC:Q8N7E2 CBLL2
Reference Transcript
RefSeq:NM_152577.3 CBLL2
Other Identifiers
11740742_at
1552967_PM_at
1552967_at
158506
17102087
3971519
3971520
3971521
8166433
A_14_P128785
A_14_P200636
A_23_P431912
A_24_P31875
GE498982
GO:0003824
GO:0005515
GO:0005737
GO:0007155
GO:0016567
GO:0016740
GO:0030155
GO:0036211
GO:0046872
GO:0061630
GO:0140096
HMNXSV003012040
Hs2.132485.1.S1_3p_at
Hs2.132485.1.S1_3p_s_at
ILMN_1811098
PH_hs_0031747
TC0X000104.hg
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
Cbll1 [cytosol]
(Mus musculus)
Cbll1 [cytosol]
(Rattus norvegicus)
CBLL1 [cytosol]
(Bos taurus)
CBLL1 [cytosol]
(Canis familiaris)
CBLL1 [cytosol]
(Sus scrofa)
ZNF645 [cytosol]
(Gallus gallus)
ZNF645 [cytosol]
(Plasmodium falciparum)
Hakai [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_689790.1
OpenTargets
ENSG00000175809
IntEnz
2.3.2.27
GeneCards
Q8N7E2
HPA
ENSG00000175809-CBLL2
Ensembl
ENSG00000175809
,
ENST00000323684
,
ENSP00000323348
PRO
Q8N7E2
Pharos - Targets
Q8N7E2
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