GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region

Stable Identifier
R-HSA-8851632
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Golgi lumen, extracellular region
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GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region
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Once fibroblast growth factor 23 (FGF23, aka phosphatonin) is glycosylated by GALNT3, it is secreted from the cell (Kato et al. 2006).

Literature References
PubMed ID Title Journal Year
16638743 Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation

Kato, K, Jeanneau, C, Tarp, MA, Benet-Pages, A, Lorenz-Depiereux, B, Bennett, EP, Mandel, U, Strom, TM, Clausen, H

J. Biol. Chem. 2006
Participants
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Orthologous Events
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Bos taurus)
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Caenorhabditis elegans)
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Canis familiaris)
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Danio rerio)
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Drosophila melanogaster)
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Gallus gallus)
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Mus musculus)
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Rattus norvegicus)
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Sus scrofa)
GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Xenopus tropicalis)
Authored
Jassal, B  (2016-01-08)
Reviewed
Hansen, L  (2016-01-15)
Joshi, HJ  (2016-01-15)
Created
Jassal, B  (2016-01-08)