GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region

Stable Identifier
R-HSA-8851632
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Once fibroblast growth factor 23 (FGF23, aka phosphatonin) is glycosylated by GALNT3, it is secreted from the cell (Kato et al. 2006).

Literature References
PubMed ID Title Journal Year
16638743 Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation

Kato, K, Jeanneau, C, Tarp, MA, Benet-Pages, A, Lorenz-Depiereux, B, Bennett, EP, Mandel, U, Strom, TM, Clausen, H

J. Biol. Chem. 2006
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created