Reactome | Release of GNB5:RGS dimers from CCT/TRiC

Release of GNB5:RGS dimers from CCT/TRiC

Stable Identifier

R-HSA-8850539

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cytosol, plasma membrane

ReviewStatus

5/5

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Release of GNB5:RGS dimers from CCT/TRiC

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Dimers of folded G-protein beta 5 subunit (GNB5) and a RGS protein RGS7, RSG9, and probably RGS6 or RGS11, are released from the CCT/TRiC chaperonin complex (Howlett et al. 2009, Tracy et al. 2015).

Literature References

PubMed ID	Title	Journal	Year
19376773	Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity Howlett, AC, Gray, AJ, Hunter, JM, Willardson, BM	J. Biol. Chem.	2009
25659125	Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling Tracy, CM, Kolesnikov, AV, Blake, DR, Chen, CK, Baehr, W, Kefalov, VJ, Willardson, BM	PLoS ONE	2015