PDCL promotes G-protein beta 5 folding

Stable Identifier
R-HSA-8850534
Type
Reaction [dissociation]
Species
Homo sapiens
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PDCL (PhLP1) increases stability of the G-protein beta 5 subunit (GNB5), presumably by assisting with the proper folding of GNB5, but does not release folded GNB5 from the TRiC/CCT chaperonin (Howlett et al. 2009).

Literature References
PubMed ID Title Journal Year
19376773 Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity

Howlett, AC, Gray, AJ, Hunter, JM, Willardson, BM

J. Biol. Chem. 2009
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