SALMs1-3 bind each other in cis interactions

Stable Identifier
R-HSA-8849900
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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SALM1, SALM2, and SALM3 form homo- and heteromeric complexes in a cis manner. These SALMs 1-3 coimmunoprecipitate with each other in extracts from brain. Whether the homo and heteromeric complexes formed between SALMs 1-3 contribute to synapse formation or neurite outgrowth remains to be determined (Seabold et al. 2008).

Literature References
PubMed ID Title Journal Year
18227064 The SALM family of adhesion-like molecules forms heteromeric and homomeric complexes

Seabold, GK, Wang, PY, Chang, K, Wang, CY, Wang, YX, Petralia, RS, Wenthold, RJ

J. Biol. Chem. 2008
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