SALMs1-3 bind each other in cis interactions

Stable Identifier
R-HSA-8849900
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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SALMs1-3 bind each other in cis interactions
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SALM1, SALM2, and SALM3 form homo- and heteromeric complexes in a cis manner. These SALMs 1-3 coimmunoprecipitate with each other in extracts from brain. Whether the homo and heteromeric complexes formed between SALMs 1-3 contribute to synapse formation or neurite outgrowth remains to be determined (Seabold et al. 2008).

Literature References
PubMed ID Title Journal Year
18227064 The SALM family of adhesion-like molecules forms heteromeric and homomeric complexes

Wang, YX, Wang, CY, Wang, PY, Wenthold, RJ, Petralia, RS, Chang, K, Seabold, GK

J. Biol. Chem. 2008
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Orthologous Events
SALMs1-3 bind each other in cis interactions (Bos taurus)
SALMs1-3 bind each other in cis interactions (Canis familiaris)
SALMs1-3 bind each other in cis interactions (Danio rerio)
SALMs1-3 bind each other in cis interactions (Drosophila melanogaster)
SALMs1-3 bind each other in cis interactions (Gallus gallus)
SALMs1-3 bind each other in cis interactions (Mus musculus)
SALMs1-3 bind each other in cis interactions (Rattus norvegicus)
SALMs1-3 bind each other in cis interactions (Sus scrofa)
SALMs1-3 bind each other in cis interactions (Xenopus tropicalis)
Authored
Garapati, P V  (2015-12-18)
Reviewed
Kim, E  (2016-02-04)
Petralia, RS  (2016-05-17)
Seabold, GK  (2016-05-17)
Created
Garapati, P V  (2015-12-18)
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