Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
CORT(89-105) [extracellular region]
Stable Identifier
R-HSA-8849392
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Cortistatin-17, CORT_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Somatostatin receptor:somatostatin [plasma membrane] (Homo sapiens)
Somatostatin, cortistatin [extracellular region] (Homo sapiens)
CORT(89-105) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Somatostatin receptor:somatostatin [plasma membrane] (Homo sapiens)
Somatostatin, cortistatin [extracellular region] (Homo sapiens)
CORT(89-105) [extracellular region] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Somatostatin receptor:somatostatin [plasma membrane] (Homo sapiens)
Somatostatin, cortistatin [extracellular region] (Homo sapiens)
CORT(89-105) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Somatostatin receptor:somatostatin [plasma membrane] (Homo sapiens)
Somatostatin, cortistatin [extracellular region] (Homo sapiens)
CORT(89-105) [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Somatostatin receptor:somatostatin [plasma membrane] (Homo sapiens)
Somatostatin, cortistatin [extracellular region] (Homo sapiens)
CORT(89-105) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Somatostatin receptor:somatostatin [plasma membrane] (Homo sapiens)
Somatostatin, cortistatin [extracellular region] (Homo sapiens)
CORT(89-105) [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Somatostatin receptors bind somatostatin and cortistatin (Homo sapiens)
Somatostatin receptor:somatostatin [plasma membrane] (Homo sapiens)
Somatostatin, cortistatin [extracellular region] (Homo sapiens)
CORT(89-105) [extracellular region] (Homo sapiens)
Somatostatin, cortistatin [extracellular region] (Homo sapiens)
CORT(89-105) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00230 CORT
Gene Names
CORT, UNQ307/PRO350
Chain
signal peptide:1-18, propeptide:19-74, peptide:77-105, peptide:89-105
Reference Genes
BioGPS Gene:1325 CORT
COSMIC (genes):CORT CORT
CTD Gene:1325 CORT
dbSNP Gene:1325 CORT
ENSEMBL:ENSG00000241563.4 CORT
HGNC:2257 CORT
KEGG Gene (Homo sapiens):1325 CORT
Monarch:1325 CORT
NCBI Gene:1325 CORT
OMIM:602784 CORT
UCSC:O00230 CORT
Reference Transcript
RefSeq:NM_001302.4 CORT
Other Identifiers
0005860377
11732668_a_at
11732669_x_at
1325
210182_PM_at
210182_at
2319853
2319854
2319855
2319856
2319858
2319859
2319860
2319861
2319862
2319863
2319864
36016_at
A_23_P258164
A_24_P246926
GE54121
GO:0000712
GO:0001664
GO:0003682
GO:0005179
GO:0005184
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0006260
GO:0006310
GO:0007059
GO:0007193
GO:0007268
GO:0022414
GO:0023052
GO:0031297
GO:0032991
GO:0043226
GO:0043240
GO:0045202
GO:0071821
GO:0098772
GO:0140013
HMNXSV003042679
ILMN_1685575
ILMN_2071186
PH_hs_0024898
g2055231_3p_at
g2055231_3p_x_at
Participates
as a member of
Somatostatin, cortistatin [extracellular region] (Homo sapiens)
Inferred To
CORT [extracellular region]
(Bos taurus)
CORT [extracellular region]
(Sus scrofa)
SS2 [extracellular region]
(Gallus gallus)
zgc:153708 [extracellular region]
(Danio rerio)
Cort [extracellular region]
(Mus musculus)
Cross References
RefSeq
NP_001293.3
OpenTargets
ENSG00000241563
GeneCards
O00230
HPA
ENSG00000241563-CORT
Ensembl
ENSP00000366248
,
ENSG00000241563
,
ENST00000377049
PRO
O00230
Pharos - Targets
O00230
PDB
7VV4
,
7VDL
HMDB Protein
HMDBP02623
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text