Reactome | THOC3 [nucleoplasm]

THOC3 [nucleoplasm]

Stable Identifier

R-HSA-8849121

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

THO complex subunit 3, THOC3_HUMAN

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - RNA Polymerase II Transcription Termination (Homo sapiens)
    - Cleavage of mRNA at the 3'-end (Homo sapiens)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Homo sapiens)
        
        THO complex [nucleoplasm] (Homo sapiens)
        
        THOC3 [nucleoplasm] (Homo sapiens)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Homo sapiens)
        
        THO complex [nucleoplasm] (Homo sapiens)
        
        THOC3 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96J01 THOC3

Gene Names

THOC3

Chain

initiator methionine:1, chain:2-351

Reference Genes

BioGPS Gene:84321 THOC3

COSMIC (genes):THOC3 THOC3

CTD Gene:84321 THOC3

dbSNP Gene:84321 THOC3

ENSEMBL:ENSG00000051596 THOC3

HGNC:19072 THOC3

KEGG Gene (Homo sapiens):84321 THOC3

Monarch:84321 THOC3

NCBI Gene:84321 THOC3

OMIM:606929 THOC3

UCSC:Q96J01 THOC3

Reference Transcript

RefSeq:NM_032361.3 THOC3

Other Identifiers

0005360324

11756139_s_at

11760126_at

224623_at

2843418

2843419

2843420

2843422

2843424

2843425

2843426

2843428

2843429

2843430

2843431

2843432

2843433

2843434

2843435

2843436

2888115

2888116

2888117

2888118

2888119

2888120

2888121

2888122

2888123

2888124

2888128

2888130

2888131

2888132

2888133

2888134

57089_at

8110408

8115886

84321

A_33_P3336642

GE56994

GO:0000346

GO:0000445

GO:0000781

GO:0003674

GO:0003723

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0006397

GO:0006405

GO:0006406

GO:0006810

GO:0006913

GO:0008150

GO:0008380

GO:0015031

GO:0016607

GO:0031124

GO:0032991

GO:0034641

GO:0043226

GO:0044403

GO:0046784

GO:0051028

HMNXSV003032962

HMNXSV003056578

Hs.19574.0.S1_3p_at

ILMN_1688903

ILMN_1691949

ILMN_1813246

ILMN_2415926

PH_hs_0027092

PH_hs_0037305

TC05001024.hg

TC05002766.hg

Participates

as a component of

THO complex [nucleoplasm] (Homo sapiens)

Inferred To

AAC3 [nucleoplasm] (Dictyostelium discoideum)

Thoc3 [nucleoplasm] (Mus musculus)

Thoc3 [nucleoplasm] (Rattus norvegicus)

THOC3 [nucleoplasm] (Canis familiaris)

THOC3 [nucleoplasm] (Gallus gallus)

THOC3 [nucleoplasm] (Schizosaccharomyces pombe)

THOC3 [nucleoplasm] (Sus scrofa)

THOC3 [nucleoplasm] (Xenopus tropicalis)

thoc3 [nucleoplasm] (Danio rerio)

tex [nucleoplasm] (Drosophila melanogaster)

thoc-3 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_115737.1

OpenTargets

ENSG00000051596

GeneCards

Q96J01

HPA

ENSG00000051596-THOC3

Ensembl

ENST00000265097, ENSP00000265097, ENSP00000422243, ENST00000513482, ENSG00000051596

PRO

Q96J01

Pharos - Targets

Q96J01

PDB

7APK

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