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KHDRBS2 [nucleoplasm]
Stable Identifier
R-HSA-8849028
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
KH domain-containing, RNA-binding, signal transduction-associated protein 2, Sam68-like mammalian protein 1, SLM1, SLM-1
Locations in the PathwayBrowser for interactor UniProt:Q8NEC5 CATSPER1
Expand all
Signal Transduction (Homo sapiens)
Signaling by Non-Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PTK6 (Homo sapiens)
PTK6 Regulates Proteins Involved in RNA Processing (Homo sapiens)
PTK6 phosphorylates KHDRBS2 (Homo sapiens)
KHDRBS2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5VWX1 KHDRBS2
Gene Names
KHDRBS2, SLM1
Chain
chain:1-349
Reference Genes
BioGPS Gene:202559 KHDRBS2
COSMIC (genes):KHDRBS2 KHDRBS2
CTD Gene:202559 KHDRBS2
dbSNP Gene:202559 KHDRBS2
ENSEMBL:ENSG00000112232 KHDRBS2
ENSEMBL_homo_sapiens_GENE:ENSG00000112232.10 KHDRBS2
HGNC:18114 KHDRBS2
KEGG Gene (Homo sapiens):202559 KHDRBS2
Monarch:202559 KHDRBS2
NCBI Gene:202559 KHDRBS2
OMIM:610487 KHDRBS2
UCSC:Q5VWX1 KHDRBS2
Reference Transcript
RefSeq:NM_152688.3 KHDRBS2
Other Identifiers
11735663_at
11747846_s_at
17020499
202559
215527_PM_at
215527_at
2959052
2959053
2959054
2959055
2959059
2959069
2959086
2959087
2959091
2959097
2959104
2959110
2959111
2959112
2959120
32024_at
8127370
A_23_P366453
GO:0000381
GO:0003676
GO:0003723
GO:0003729
GO:0005515
GO:0005634
GO:0005654
GO:0006397
GO:0008143
GO:0008266
GO:0016071
GO:0017124
GO:0042169
GO:0043226
GO:0048024
Hs.226014.0.S1_3p_at
PH_hs_0032115
TC06001842.hg
Participates
as an input of
PTK6 phosphorylates KHDRBS2 (Homo sapiens)
Other forms of this molecule
p-Y-KHDRBS2 [nucleoplasm]
Inferred To
Dmel\CG4021 [nucleoplasm]
(Drosophila melanogaster)
qkr58E-2 [nucleoplasm]
(Drosophila melanogaster)
qkr58E-1 [nucleoplasm]
(Drosophila melanogaster)
khdrbs2 [nucleoplasm]
(Danio rerio)
khdrbs2 [nucleoplasm]
(Xenopus tropicalis)
Khdrbs2 [nucleoplasm]
(Mus musculus)
Khdrbs2 [nucleoplasm]
(Rattus norvegicus)
qkr58E-3 [nucleoplasm]
(Drosophila melanogaster)
cg10384 [nucleoplasm]
(Drosophila melanogaster)
KHDRBS2 [nucleoplasm]
(Bos taurus)
KHDRBS2 [nucleoplasm]
(Canis familiaris)
KHDRBS2 [nucleoplasm]
(Gallus gallus)
KHDRBS2 [nucleoplasm]
(Sus scrofa)
cg3927 [nucleoplasm]
(Drosophila melanogaster)
qkr54B [nucleoplasm]
(Drosophila melanogaster)
Homologues of KHDRBS2 [nucleoplasm]
(Drosophila melanogaster)
nsr [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_689901.2
OpenTargets
ENSG00000112232
HPA
ENSG00000112232-KHDRBS2
GeneCards
Q5VWX1
Ensembl
ENSP00000281156
,
ENST00000281156
,
ENSG00000112232
PRO
Q5VWX1
Pharos - Targets
Q5VWX1
Interactors (67)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P38159 RBMX
2
RBMX [cytosol]
(R-HSA-9715135)
RBMX [nucleoplasm]
(R-HSA-71939)
0.852
10
UniProt:P98179 RBM3
0.83
8
UniProt:Q8WWY3 PRPF31
1
PRPF31 [nucleoplasm]
(R-HSA-6806772)
0.795
8
UniProt:P29597 TYK2
5
p-TYK2 [cytosol]
(R-HSA-8950424)
p-Y-TYK2 [cytosol]
(R-HSA-6784366)
TYK2 [cytosol]
(R-HSA-877348)
p-Y1054,Y1055-TYK2 [cytosol]
(R-HSA-909682)
p-Y1054-TYK2 [cytosol]
(R-HSA-1112598)
0.781
7
UniProt:O75525 KHDRBS3
2
KHDRSB3 [nucleoplasm]
(R-HSA-8849040)
p-Y-KHDRSB3 [nucleoplasm]
(R-HSA-8849035)
0.743
6
UniProt:Q96MU7 YTDC1
0.718
6
UniProt:P79522 PRR3
0.718
6
UniProt:Q9NQX5 NPDC1
1
NPDC1 [plasma membrane]
(R-HSA-8959647)
0.718
6
UniProt:O00560 SDCBP
3
SDCBP [extracellular region]
(R-HSA-6806206)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [cytosol]
(R-HSA-373639)
0.718
6
UniProt:Q92608 DOCK2
3
DOCK2 [specific granule lumen]
(R-HSA-6799558)
DOCK2 [extracellular region]
(R-HSA-6806310)
DOCK2 [cytosol]
(R-HSA-200938)
0.718
6
UniProt:Q8NEC5 CATSPER1
1
CATSPER1 [plasma membrane]
(R-HSA-2534335)
0.718
6
UniProt:Q13882 PTK6
5
p-Y342-PTK6 [nucleoplasm]
(R-HSA-8848937)
p-Y342,Y447-PTK6 [cytosol]
(R-HSA-8849103)
p-Y351-PTK6 [cytosol]
(R-HSA-8857570)
PTK6 [cytosol]
(R-HSA-8848000)
p-Y342-PTK6 [cytosol]
(R-HSA-8848007)
0.666
4
UniProt:P61978-2 HNRNPK
0.666
4
UniProt:Q14011 CIRBP
0.666
4
UniProt:P02008 HBAZ
0.666
4
UniProt:Q6VB84 FX4L3
0.556
3
UniProt:Q03014 HHEX
0.556
3
UniProt:P18075 BMP7
2
BMP7(30-292) [extracellular region]
(R-HSA-206223)
BMP7 [extracellular region]
(R-HSA-206257)
0.556
3
UniProt:Q9P0T4 ZN581
0.556
3
UniProt:Q13330 MTA1
2
MTA1 [nucleoplasm]
(R-HSA-3465550)
polySUMO2,3-K509-MTA1 [nucleoplasm]
(R-HSA-3465537)
0.556
3
UniProt:Q6ZNH5 ZN497
0.556
3
UniProt:P98175 RBM10
1
RBM10 [nucleoplasm]
(R-HSA-9770262)
0.556
3
IntAct:EBI-16428938 CCSB ISOFORM ID
0.556
3
UniProt:Q9Y3Y2 CHTOP
1
CHTOP [nucleoplasm]
(R-HSA-8849147)
0.556
3
UniProt:Q9Y3Y2-3 CHTOP
0.556
3
UniProt:O43390 HNRNPR
1
HNRNPR [nucleoplasm]
(R-HSA-71951)
0.556
3
UniProt:Q96EG3 ZN837
0.556
3
UniProt:Q96AH0 NABP1
1
NABP1 [nucleoplasm]
(R-HSA-6814919)
0.556
3
UniProt:Q8WTP8 AEN
0.556
3
UniProt:A0A0S2Z5X4 A0A0S2Z5X4
0.556
3
IntAct:EBI-10188384 57727
0.556
3
UniProt:Q8NE01 CNNM3
0.556
3
UniProt:Q5D0E6-2 DALRD3
0.556
3
UniProt:Q8TBE0 BAHD1
0.556
3
UniProt:P0DMN0 SULT1A4
1
SULT1A4 [cytosol]
(R-HSA-8959974)
0.556
3
UniProt:P38340 NTM1
0.556
3
UniProt:P40938 RFC3
1
RFC3 [nucleoplasm]
(R-HSA-68431)
0.556
3
IntAct:EBI-10207182 255167
0.556
3
UniProt:P36084
2
MUD2 [nucleoplasm]
(R-SCE-9630011)
MUD2 [nucleoplasm]
(R-SCE-71987)
0.556
3
UniProt:Q9UQ90 SPG7
1
SPG7 [mitochondrial inner membrane]
(R-HSA-8953712)
0.556
3
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.556
3
UniProt:Q8TAI1 TYMOS
0.556
3
UniProt:G3V1X1 G3V1X1
0.556
3
UniProt:Q96PK6 RBM14
1
RBM14 [nucleoplasm]
(R-HSA-8938345)
0.556
3
UniProt:P40507 AIR1
0.556
3
UniProt:Q8IXW0 LMTD2
0.556
3
IntAct:EBI-22318346 CCSB ORF ID
0.556
3
UniProt:Q01844 EWS
0.553
2
UniProt:Q5VWX1 KHDRBS2
2
KHDRBS2 [nucleoplasm]
(R-HSA-8849028)
p-Y-KHDRBS2 [nucleoplasm]
(R-HSA-8849031)
0.553
2
UniProt:Q07666 KHDRBS1
3
p-Y435,Y440,Y443-KHDRBS1 [nucleoplasm]
(R-HSA-8848970)
p-Y435,Y440,Y443-KHDRBS1 [cytosol]
(R-HSA-8848995)
KHDRBS1 [nucleoplasm]
(R-HSA-8848941)
0.547
3
UniProt:P09110 ACAA1
6
ACAA1(1-26) [peroxisomal matrix]
(R-HSA-9033534)
ACAA1(1-424) [peroxisomal matrix]
(R-HSA-9033517)
ACAA1(1-424) [cytosol]
(R-HSA-9033127)
ACAA1 [extracellular region]
(R-HSA-6799680)
ACAA1 [specific granule lumen]
(R-HSA-6799608)
ACAA1 [peroxisomal matrix]
(R-HSA-390238)
0.527
2
UniProt:Q13616 CUL1
3
G76-NEDD8-K720-CUL1 [cytosol]
(R-HSA-8952519)
CUL1 [nucleoplasm]
(R-HSA-187551)
CUL1 [cytosol]
(R-HSA-174230)
0.527
3
UniProt:Q5MNZ6 WDR45B
1
WDR45B [cytosol]
(R-HSA-5678303)
0.527
2
UniProt:P40121 CAPG
0.527
2
UniProt:Q03426 MVK
1
MVK [cytosol]
(R-HSA-191375)
0.527
2
UniProt:Q15022 SUZ12
2
SUZ12 [nucleoplasm]
(R-HSA-212217)
monoSUMO1-K75-SUZ12 [nucleoplasm]
(R-HSA-4615932)
0.527
2
UniProt:P27361 MAPK3
6
MAPK3 [endoplasmic reticulum lumen]
(R-HSA-9636295)
p-T202-MAPK3 [cytosol]
(R-HSA-9635775)
MAPK3 [nucleoplasm]
(R-HSA-73724)
MAPK3 [cytosol]
(R-HSA-59284)
p-T202,Y204-MAPK3 [cytosol]
(R-HSA-109842)
p-T202,Y204-MAPK3 [nucleoplasm]
(R-HSA-112359)
0.527
2
UniProt:Q2NKJ3 CTC1
1
CTC1 [nucleoplasm]
(R-HSA-9668825)
0.527
2
UniProt:Q9P2K6 KLHL42
1
KLHL42 [cytosol]
(R-HSA-8863204)
0.527
2
UniProt:Q9UJ70 NAGK
1
NAGK [cytosol]
(R-HSA-6803742)
0.527
2
UniProt:O95352 ATG7
14
ATG7 [secretory granule lumen]
(R-HSA-6801316)
ATG7 [extracellular region]
(R-HSA-6806451)
ATG7 [ficolin-1-rich granule lumen]
(R-HSA-6801293)
ATG7(1-693)-BRAF(381-766) fusion [cytosol]
(R-HSA-6802272)
ATG7(1-693)-p-BRAF(381-766) fusion [cytosol]
(R-HSA-6802517)
CysO572-ATG7-MAP1LC3B [cytosol]
(R-HSA-9820410)
CysO572-ATG7-GARABAPL2 [cytosol]
(R-HSA-9820413)
CysO572-ATG7-GARABAP [cytosol]
(R-HSA-9820417)
CysO572-ATG7-GARABAPL1 [cytosol]
(R-HSA-9820406)
CysO572-ATG7-MAP1LC3C [cytosol]
(R-HSA-9820407)
CysO572-ATG7-MAP1LC3A [cytosol]
(R-HSA-9820421)
CysO572-ATG7-GARABAPL3 [cytosol]
(R-HSA-9820420)
CysO572-ATG7 [cytosol]
(R-HSA-5683584)
ATG7 [cytosol]
(R-HSA-947867)
0.527
2
UniProt:P55318 FOXA3
1
FOXA3 [nucleoplasm]
(R-HSA-211484)
0.527
2
UniProt:Q93009 USP7
2
USP7 [cytosol]
(R-HSA-8853511)
USP7 [nucleoplasm]
(R-HSA-3215278)
0.527
3
UniProt:Q86U90 YRDC
0.527
2
UniProt:Q709F0 ACAD11
1
ACAD11 [mitochondrial inner membrane]
(R-HSA-5695987)
0.527
2
UniProt:Q92530 PSMF1
1
PSMF1 [cytosol]
(R-HSA-68818)
0.488
2
UniProt:O75791 GRAP2
1
GRAP2 [cytosol]
(R-HSA-202367)
0.488
2
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