Reactome | AHSG [platelet alpha granule lumen]

AHSG [platelet alpha granule lumen]

Stable Identifier

R-HSA-8848910

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

platelet alpha granule lumen

Synonyms

Alpha-2-HS-glycoprotein, FETUA_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P02765 AHSG

Gene Names

AHSG, FETUA, PRO2743

Chain

signal peptide:1-18, chain:19-300, propeptide:301-340, chain:341-367

Reference Genes

BioGPS Gene:197 AHSG

COSMIC (genes):AHSG AHSG

CTD Gene:197 AHSG

dbSNP Gene:197 AHSG

ENSEMBL:ENSG00000145192 AHSG

HGNC:349 AHSG

KEGG:hsa:197 AHSG

Monarch:197 AHSG

NCBI Gene:197 AHSG

OMIM:138680 AHSG

UCSC:P02765 AHSG

Reference Transcript

RefSeq:NM_001622.2 AHSG

Other Identifiers

11716357_a_at

11746474_a_at

16949311

197

204551_PM_s_at

204551_s_at

210929_PM_s_at

210929_s_at

2656599

2656600

2656601

2656602

2656605

2656606

2656607

2656608

2656609

2656610

2656611

2656612

2656613

2656615

2656617

2656618

2656619

2656620

2656621

2656622

36621_at

79306_at

8084648

A_14_P126129

A_23_P155509

A_23_P155514

GE57847

GE87113

GO:0001501

GO:0001503

GO:0004866

GO:0004869

GO:0005515

GO:0005576

GO:0005615

GO:0005788

GO:0005794

GO:0006907

GO:0006953

GO:0006954

GO:0016192

GO:0019210

GO:0030312

GO:0030500

GO:0030502

GO:0031012

GO:0031093

GO:0034774

GO:0043226

GO:0046627

GO:0048856

GO:0050727

GO:0050766

GO:0062023

GO:0070062

GO:0072562

GO:0098772

HMNXSV003043558

ILMN_1730625

M16961_at

PH_hs_0016144

TC03001020.hg

g4502004_3p_a_at

g4502004_3p_s_at

Participates

as a member of

Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)

Other forms of this molecule

AHSG [extracellular region]

AHSG [secretory granule lumen]

p-AHSG [endoplasmic reticulum lumen]

AHSG [endoplasmic reticulum lumen]

Inferred To

Ahsg [platelet alpha granule lumen] (Mus musculus)

Ahsg [platelet alpha granule lumen] (Rattus norvegicus)

ahsg1 [platelet alpha granule lumen] (Danio rerio)

AHSG [platelet alpha granule lumen] (Bos taurus)

AHSG [platelet alpha granule lumen] (Canis familiaris)

AHSG [platelet alpha granule lumen] (Gallus gallus)

AHSG [platelet alpha granule lumen] (Sus scrofa)

ahsg [platelet alpha granule lumen] (Xenopus tropicalis)

Cross References

RefSeq

NP_001613.2

ENSEMBL

ENST00000411641, ENSP00000393887

OpenTargets

ENSG00000145192

HPA

ENSG00000145192-AHSG

PRO

P02765

Pharos - Targets

P02765

GlyGen

P02765

HMDB Protein

HMDBP07684

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.527	3
UniProt:Q16659 MAPK6 gene	6	p-3S,T MAPK6 [nucleoplasm] (R-HSA-5692665) MAPK6 [nucleoplasm] (R-HSA-5692686) p-S189 MAPK6 [nucleoplasm] (R-HSA-5687015) p-S189 MAPK6 [cytosol] (R-HSA-5687019) MAPK6 [cytosol] (R-HSA-5686979) ub-MAPK6 [cytosol] (R-HSA-5687000)	0.527	2
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.527	4

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