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APLP2 [plasma membrane]
Stable Identifier
R-HSA-8848902
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Amyloid-like protein 2, APLP2_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Surface deployment of platelet alpha granule membrane components (Homo sapiens)
Platelet alpha granule membrane components that are released on degranulation [plasma membrane] (Homo sapiens)
APLP2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q06481 APLP2
Gene Names
APLP2, APPL2
Chain
signal peptide:1-31, chain:32-763
Reference Genes
COSMIC (genes):APLP2 APLP2
COSMIC (genes):APPL2 APLP2
dbSNP Gene:334 APLP2
ENSEMBL:ENSG00000084234 APLP2
Participates
as a member of
Platelet alpha granule membrane components that are released on degranulation [plasma membrane] (Homo sapiens)
Other forms of this molecule
APLP2 [platelet alpha granule membrane]
p-APLP2 [endoplasmic reticulum lumen]
APLP2 [endoplasmic reticulum lumen]
Inferred To
APLP2 [plasma membrane]
(Bos taurus)
APLP2 [plasma membrane]
(Caenorhabditis elegans)
APLP2 [plasma membrane]
(Canis familiaris)
APLP2 [plasma membrane]
(Gallus gallus)
APLP2 [plasma membrane]
(Mus musculus)
APLP2 [plasma membrane]
(Rattus norvegicus)
APLP2 [plasma membrane]
(Sus scrofa)
Appl [plasma membrane]
(Drosophila melanogaster)
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05412 JUN
4
JUN [nucleoplasm]
(R-HSA-450250)
p-S63,S73-JUN [nucleoplasm]
(R-HSA-450237)
JUN [cytosol]
(R-HSA-168194)
p-S63,S73-JUN [cytosol]
(R-HSA-8868682)
0.573
3
UniProt:O00213 APBB1
1
APBB1 [nucleoplasm]
(R-HSA-5683987)
0.547
3
UniProt:P05067-4 APP
2
APP (535-695) [cytosol]
(R-HSA-9839084)
APP [mitochondrial inner membrane]
(R-HSA-9839060)
0.544
2
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