Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PHACTR2 [platelet alpha granule membrane]
Stable Identifier
R-HSA-8848893
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
platelet alpha granule membrane
Synonyms
Phosphatase and actin regulator 2, PHAR2_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Surface deployment of platelet alpha granule membrane components (Homo sapiens)
Platelet alpha granule membrane components that are released on degranulation [platelet alpha granule membrane] (Homo sapiens)
PHACTR2 [platelet alpha granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75167 PHACTR2
Gene Names
PHACTR2, C6orf56, KIAA0680
Chain
initiator methionine:, initiator methionine:, chain:1-634
Reference Genes
BioGPS Gene:9749 PHACTR2
COSMIC (genes):PHACTR2 PHACTR2
CTD Gene:9749 PHACTR2
dbSNP Gene:9749 PHACTR2
ENSEMBL:ENSG00000112419 PHACTR2
HGNC:20956 PHACTR2
KEGG:hsa:9749 PHACTR2
Monarch:9749 PHACTR2
NCBI Gene:9749 PHACTR2
OMIM:608724 PHACTR2
UCSC:O75167 PHACTR2
Reference Transcript
RefSeq:NM_001100165.1 PHACTR2
RefSeq:NM_014721.2 PHACTR2
RefSeq:NM_001100164.1 PHACTR2
RefSeq:NM_001100166.1 PHACTR2
Other Identifiers
11739709_a_at
11739710_a_at
11739711_a_at
11739712_a_at
11740045_a_at
11740688_a_at
11740689_a_at
17013223
17013247
17013249
204047_PM_s_at
204047_s_at
204048_PM_s_at
204048_s_at
204049_PM_s_at
204049_s_at
227947_PM_at
227947_at
244774_PM_at
244774_at
2928931
2928932
2928933
2928940
2928941
2928948
2928949
2928950
2928956
2928957
2928962
2928963
2928964
2928965
2928966
2928967
2928972
2928973
2928974
2928975
2928976
2928978
2928979
2928983
2928985
2928986
2928987
2928988
2928989
2928993
2928994
2928997
2928998
2928999
2929000
2929001
2929002
2929037
2929038
2929039
2929040
2929041
41364_r_at
43459_at
48439_at
77851_at
8122426
9749
A_14_P109250
A_23_P111240
A_24_P726336
A_33_P3321050
GE53387
GE876792
GO:0003779
GO:0004864
GO:0005515
GO:0005886
GO:0007010
GO:0008092
GO:0016020
GO:0030036
GO:0031092
GO:0098772
HMNXSV003043636
Hs.102471.0.S1_3p_a_at
Hs.102471.0.S2_3p_a_at
Hs.271593.0.A1_3p_at
Hs.323117.0.A1_3p_at
ILMN_1790533
PH_hs_0005681
TC06004098.hg
g7662247_3p_a_at
Participates
as a member of
Platelet alpha granule membrane components that are released on degranulation [platelet alpha granule membrane] (Homo sapiens)
Other forms of this molecule
PHACTR2 [plasma membrane]
Inferred To
Homologues of PHACTR2 [platelet alpha granule membrane]
(Saccharomyces cerevisiae)
PHACTR2 [platelet alpha granule membrane]
(Bos taurus)
PHACTR2 [platelet alpha granule membrane]
(Canis familiaris)
PHACTR2 [platelet alpha granule membrane]
(Gallus gallus)
PHACTR2 [platelet alpha granule membrane]
(Saccharomyces cerevisiae)
PHACTR2 [platelet alpha granule membrane]
(Sus scrofa)
AFR1 [platelet alpha granule membrane]
(Saccharomyces cerevisiae)
Phactr2 [platelet alpha granule membrane]
(Mus musculus)
Phactr2 [platelet alpha granule membrane]
(Rattus norvegicus)
phactr2 [platelet alpha granule membrane]
(Xenopus tropicalis)
phac-1 [platelet alpha granule membrane]
(Caenorhabditis elegans)
BNI4 [platelet alpha granule membrane]
(Saccharomyces cerevisiae)
CG12604 [platelet alpha granule membrane]
(Drosophila melanogaster)
Cross References
ENSEMBL
ENSG00000112419
,
ENST00000427704
,
ENSP00000305530
,
ENST00000367582
,
ENST00000305766
,
ENSP00000417038
,
ENSP00000391763
,
ENST00000440869
,
ENSP00000356554
OpenTargets
ENSG00000112419
GeneCards
PHACTR2
HPA
ENSG00000112419-PHACTR2
PRO
O75167
Pharos - Targets
O75167
GlyGen
O75167
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P60709 ACTB
5
ACTB [plasma membrane]
(R-HSA-196016)
ACTB [lysosomal membrane]
(R-HSA-196160)
ACTB [cytosol]
(R-HSA-201861)
ACTB [nucleoplasm]
(R-HSA-3321990)
Unfolded ACTB [cytosol]
(R-HSA-390462)
0.643
3
UniProt:P62736 ACTA2
1
ACTA2 [cytosol]
(R-HSA-445792)
0.527
3
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text