PTK6 binds DOK1

Stable Identifier
R-HSA-8848774
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
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PTK6 binds DOK1
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PTK6 (BRK) binds the tumor suppressor DOK1 and this interaction involves the SH3 domain of PTK6 (Miah et al. 2014).

Literature References
PubMed ID Title Journal Year
24523872 BRK targets Dok1 for ubiquitin-mediated proteasomal degradation to promote cell proliferation and migration

Miah, S, Goel, RK, Dai, C, Kalra, N, Beaton-Brown, E, Bagu, ET, Bonham, K, Lukong, KE

PLoS ONE 2014
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
PTK6 binds DOK1 (Danio rerio)
PTK6 binds DOK1 (Drosophila melanogaster)
PTK6 binds DOK1 (Mus musculus)
PTK6 binds DOK1 (Rattus norvegicus)
PTK6 binds DOK1 (Sus scrofa)
PTK6 binds DOK1 (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2016-01-05)
Reviewed
Pires, IM  (2016-02-07)
Created
Orlic-Milacic, M  (2015-12-10)
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