Acyl-CoA-binding protein (DBI, aka ACBP) can bind medium- and long-chain acyl-CoA esters (MCFA-CoA, LCFA-CoA) with very high affinity. It is localised to the ER (and Golgi) and may function as an intracellular carrier of acyl-CoA esters (Hansen et al. 2008, Bloksgaard et al. 2014). Acyl-CoA-binding domain-containing protein 7 (ACBD7) shares around 60% sequence homology with DBI and is proposed to also bind fatty acyl-CoAs but its function is yet to be determined.
Kragelund, BB, Faergeman, NJ, Hansen, JS, Knudsen, J
Færgeman, NJ, Neess, D, Mandrup, S, Bloksgaard, M
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